Evidence map›Paper›PMID 35760729›Full record

ReviewSeminars in cell & developmental biology2023

Making a head: Neural crest and ectodermal placodes in cranial sensory development.

Alison Koontz, Hugo A Urrutia, Marianne E Bronner

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Neural Orchestration of Mandibular Development.International dental journal · 2026
    Review
  3. Article
  4. Article
  5. Core microRNAs regulate neural crest delamination and condensation in the developing trigeminal ganglion.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
  7. Elp1 function in placode-derived neurons is critical for proper trigeminal ganglion development.Developmental dynamics : an official publication of the American Association of Anatomists · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Alison KoontzDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Hugo A UrrutiaDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Marianne E BronnerDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address: mbronner@caltech.edu.
California Institute of Technology · US

Funding

Cell lineage and transcriptional analysis of the vertebrate neural plate borderR01DE027538 · NIDCR · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI Marianne Bronner · 2018 to 2026
$4.4M
Clonal analysis of the cranial neural crestR01DE027568 · NIDCR · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI BRONNER, MARIANNE · 2018 to 2022
$2.2M
Molecular mechanisms driving cessation of neural crest migration and aggregation into cranial gangliaF31DE031154 · NIDCR · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI URRUTIA, HUGO ALEXANDER · 2021 to 2025
$193k
Clonal Analysis of the Cranial Neural Crest using RIA VirusesF31DE027583 · NIDCR · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI KOONTZ, ALISON · 2017 to 2020
$137k
NIDCR NIH HHS F31 DE027583NIDCR NIH HHS F31 DE031154NIDCR NIH HHS R01 DE027538NIDCR NIH HHS R01 DE027568
6 · The paper itself

Abstract

During development of the vertebrate sensory system, many important components like the sense organs and cranial sensory ganglia arise within the head and neck. Two progenitor populations, the neural crest, and cranial ectodermal placodes, contribute to these developing vertebrate peripheral sensory structures. The interactions and contributions of these cell populations to the development of the lens, olfactory, otic, pituitary gland, and cranial ganglia are vital for appropriate peripheral nervous system development. Here, we review the origins of both neural crest and placode cells at the neural plate border of the early vertebrate embryo and investigate the molecular and environmental signals that influence specification of different sensory regions. Finally, we discuss the underlying molecular pathways contributing to the complex vertebrate sensory system from an evolutionary perspective, from basal vertebrates to amniotes.

Indexed as

Gene Expression Regulation, DevelopmentalNeural CrestAnimalsEctodermOrganogenesisVertebratesEctodermal placodeNeural crestSensory systemVertebrate evolution

Identifiers

PMID35760729
PMCPMC10224775
OpenAlexW4283451553

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.