Evidence map›Paper›PMID 35765835›Full record

ArticleProceedings. Biological sciences2022

Inbreeding depression and the probability of racing in the Thoroughbred horse.

Emmeline W Hill, Martin A Stoffel, Beatrice A McGivney, David E MacHugh, Josephine M Pemberton

Open access · hybridAbstract read
In one paragraph

Article in Proceedings. Biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

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  14. The Social and Reproductive Challenges Faced by Free-Roaming Horse (Animals : an open access journal from MDPI · 2023
    Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Emmeline W HillPlusvital Ltd, The Highline, Dún Laoghaire Industrial Estate, Pottery Road, Dún Laoghaire, Co. Dublin, Ireland.ORCID 0000-0002-1805-2250
Martin A StoffelInstitute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FL, UK.
Beatrice A McGivneyPlusvital Ltd, The Highline, Dún Laoghaire Industrial Estate, Pottery Road, Dún Laoghaire, Co. Dublin, Ireland.
David E MacHughUCD School of Agriculture and Food Science, University College Dublin, Belfield, Dublin D04 V1W8, Ireland.
Josephine M PembertonInstitute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FL, UK.
University College Dublin · IEUniversity of Edinburgh · GBPlusvital (Ireland) · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Small effective population sizes and active inbreeding can lead to inbreeding depression due to deleterious recessive mutations exposed in the homozygous state. The Thoroughbred racehorse has low levels of population genetic diversity, but the effects of genomic inbreeding in the population are unknown. Here, we quantified inbreeding based on runs of homozygosity (ROH) using 297 K SNP genotypes from 6128 horses born in Europe and Australia, of which 13.2% were unraced. We show that a 10% increase in inbreeding (

Indexed as

Inbreeding DepressionAnimalsGenome-Wide Association StudyHorsesInbreedingPolymorphism, Single NucleotideProbabilityEFNA5genomicsinbreedinginbreeding depressionracingruns of homozygosity

Identifiers

PMID35765835
PMCPMC9240673
OpenAlexW4283699753

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.