Evidence map›Paper›PMID 35766604›Full record

Trial reportArquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery2022

PROBIOTIC SUPPLEMENTATION ATTENUATES BINGE EATING AND FOOD ADDICTION 1 YEAR AFTER ROUX-EN-Y GASTRIC BYPASS: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL.

Ligia de Oliveira Carlos, Marilia Rizzon Zaparolli Ramos, Nathalia Ramori Farinha Wagner, Lineu Alberto Cavazani de Freitas, Ingrid Felicidade, Antonio Carlos Ligocki Campos

Open access · diamondAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 5 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 5 syntheses or guidelines pooled it, 35 citations in OpenAlex.

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  14. [Research progress of probiotics regulating intestinal micro-ecological environment in obese patients after bariatric surgery].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ligia de Oliveira CarlosUniversidade Federal do Paraná, Departamento de Clínica Cirúrgica - Curitiba - PR - Brazil.ORCID http://orcid.org/0000-0002-2049-4592
Marilia Rizzon Zaparolli RamosUniversidade Federal do Paraná, Departamento de Clínica Cirúrgica - Curitiba - PR - Brazil.ORCID http://orcid.org/0000-0002-5112-6979
Nathalia Ramori Farinha WagnerUniversidade Federal do Paraná, Departamento de Clínica Cirúrgica - Curitiba - PR - Brazil.ORCID http://orcid.org/0000-0003-0058-2859
Lineu Alberto Cavazani de FreitasUniversidade Federal do Paraná, Departamento de Informática - Curitiba - PR - Brazil.ORCID http://orcid.org/0000-0002-0076-6642
Ingrid FelicidadeUniversidade Estadual de Londrina, Departamento de Biologia Geral - Londrina - PR - Brazil.ORCID http://orcid.org/0000-0001-8981-2440
Antonio Carlos Ligocki CamposUniversidade Federal do Paraná, Departamento de Clínica Cirúrgica - Curitiba - PR - Brazil.ORCID http://orcid.org/0000-0001-5080-8380
Universidade Federal do Paraná · BRUniversidade Estadual de Londrina · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe use of probiotics as adjuvants in the treatment of eating disorders, known as psychobiotics, has already been investigated as a means of modulating the microbiota-gut-brain axis. This study aimed to assess the effect of probiotic supplementation on binge eating and food addiction in subjects after Roux-en-Y gastric bypass surgery.

methodsThis is a randomized, double-blind, placebo-controlled trial involving 101 patients who received probiotic (Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07) or placebo supplements for 90 days after bariatric surgery, starting on the seventh postoperative day. They were evaluated preoperatively (T0) and postoperatively at 90 days (T1) and 1 year (T2) after surgery. The Yale Food Addiction Scale (YFAS) and Binge Eating Scale (BES) were applied to assess food addiction and binge eating, respectively.

resultsBefore surgery, one-third of the patients presented with a food addiction and binge eating diagnosis. The number of symptoms of YFAS and the BES score decreased significantly in both groups at T1 compared to T0. However, a significant effect of treatment with probiotics was observed 1 year after surgery (T2). Both the number of symptoms of food addiction and the binge eating score were lower in the probiotic group than in the placebo group (p=0.037 and p=0.030, respectively).

conclusionThe use of probiotic supplementation for 90 days in the immediate postoperative period may decrease food addiction symptoms and binge eating score up to 1 year after surgery compared to controls.

Indexed as

Binge-Eating DisorderBulimiaFood AddictionGastric BypassProbioticsDietary SupplementsDouble-Blind MethodHumans

Identifiers

PMID35766604
PMCPMC9254603
OpenAlexW4285301321

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.