Evidence map›Paper›PMID 35766972›Full record

ArticleDiabetic medicine : a journal of the British Diabetic Association2022

Prescribing costs of hypoglycaemic agents and associations with metabolic control in Wales; a national analysis of primary care data.

Peter N Taylor, Qi Zhuang Siah, Omar Marei, Mia McDade-Kumar, Nasser Rachedi, Robert Bracchi, Richard Boldero, Kath Haines, Mohammed Alhadj Ali, Robert French and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Diabetic medicine : a journal of the British Diabetic Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Peter N TaylorDiabetes Research Group, Cardiff University School of Medicine, Cardiff, UK.ORCID 0000-0002-3436-422X
Qi Zhuang SiahDiabetes Research Group, Cardiff University School of Medicine, Cardiff, UK.
Omar MareiDiabetes Research Group, Cardiff University School of Medicine, Cardiff, UK.
Mia McDade-KumarDiabetes Research Group, Cardiff University School of Medicine, Cardiff, UK.
Nasser RachediDiabetes Research Group, Cardiff University School of Medicine, Cardiff, UK.
Robert BracchiAll Wales Therapeutics and Toxicology Centre, The Routledge Academic Centre, University Hospital Llandough, Cardiff, UK.
Richard BolderoAll Wales Therapeutics and Toxicology Centre, The Routledge Academic Centre, University Hospital Llandough, Cardiff, UK.
Kath HainesAll Wales Therapeutics and Toxicology Centre, The Routledge Academic Centre, University Hospital Llandough, Cardiff, UK.
Mohammed Alhadj AliDiabetes Research Group, Cardiff University School of Medicine, Cardiff, UK.
Robert FrenchDiabetes Research Group, Cardiff University School of Medicine, Cardiff, UK.
Colin M DayanDiabetes Research Group, Cardiff University School of Medicine, Cardiff, UK.
Cardiff University · GBUniversity Hospital Llandough · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThere has been a dramatic increase in hypoglycaemic agent expenditure. We assessed the variability in prescribing costs at the practice level and the relationship between expenditure and the proportion of patients achieving target glycaemic control.

methodsWe utilized national prescribing data from 406 general practices in Wales. This was compared against glycaemic control (percentage of patients achieving a HbA1c level < 59 mmol/mol in the preceding 12 months). Analyses were adjusted for the number of patients with diabetes in each general practice and the Welsh Index of Multiple Deprivation.

resultsThere was considerable heterogeneity in hypoglycaemic agent spend per patient with diabetes, Median = £289 (IQR 247-343) range £31.1-£1713. Higher total expenditure was not associated with improved glycaemic control B

conclusionsSpend on hypoglycaemic agents is highly variable between practices and increased expenditure per patient is not associated with better glycaemic control. Whilst newer, more expensive agents have additional benefits, in individuals where these advantages are more marginal widespread use of these agents has important cost implications.

Indexed as

Diabetes Mellitus, Type 2Hypoglycemic AgentsBlood GlucoseGlycated HemoglobinHumansPrimary Health CareWalesBlood GlucoseGlycated HemoglobinHypoglycemic AgentscostHbA1cHypoglycaemic agentsprimary care

Identifiers

PMID35766972
PMCPMC9545615
OpenAlexW4283720946

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.