Evidence map›Paper›PMID 35769476›Full record

ArticleFrontiers in immunology2022

B10 Cells Are Associated With Clinical Prognosis During Adult Symptomatic Acute HBV Infection.

Yali Liu, Xiaofei Du, Junfeng Lu, Lina Ma, Yi Jing, Haijing Ben, Xinyue Chen, Jing Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yali LiuThe Third Unit, Department of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing, China.
Xiaofei DuThe Third Unit, Department of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing, China.
Junfeng LuThe First Unit, Department of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing, China.
Lina MaThe First Unit, Department of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing, China.
Yi JingThe First Unit, Department of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing, China.
Haijing BenBeijing Institute of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing, China.
Xinyue ChenThe First Unit, Department of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing, China.
Jing ZhangThe Third Unit, Department of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing, China.
Beijing YouAn Hospital · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are few reports about the role of B10 cells in acute hepatitis B (AHB) infection. In this study, based on 48 acute hepatitis B infected patients, we analysis the correlation of B10 cells with HBV clinical prognosis. The results showed that B10 was positively correlated with HBsAg and HBeAg and inversely correlated with anti-HBs. The level of B10 in one week before HBsAg clearance was significantly lower than 2 weeks prior to HBsAg clearance and after 1-2 weeks of HBsAg clearance. B10 cell frequency displayed no correlation with HBV DNA; however, it showed significant temporal synchronization with hepatic inflammatory markers such as ALT. B10 level also associated with hospitalization time. These results indicated that B10 is closely related to the clinical prognosis of acute HBV infection.

Indexed as

Hepatitis BHepatitis B Surface AntigensAdultHepatitis B e AntigensHepatitis B virusHumansPrognosisHepatitis B e AntigensHepatitis B Surface AntigensacuteB10cytokinehepatitis Binterleukin-10prognosisregulatory B cell

Identifiers

PMID35769476
PMCPMC9234142
OpenAlexW4282579199

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.