Evidence map›Paper›PMID 35770683›Full record

ReviewImmunological reviews2022

The nervous system during COVID-19: Caught in the crossfire.

Nick R Natale, John R Lukens, William A Petri

Open access · bronzeAbstract readReview
In one paragraph

Review in Immunological reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Anxiety and depression symptoms among patients with long COVID: a retrospective cohort study.European archives of psychiatry and clinical neuroscience · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Acupoint stimulation for long COVID: A promising intervention:.World journal of acupuncture-moxibustion · 2023
    Review
  11. Article
  12. Article
  13. An introduction to neuroimmunology.Immunological reviews · 2022
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nick R NataleDivision of Infectious Diseases and International Health, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia, USA.
John R LukensCenter for Brain Immunology and Glia (BIG), Department of Neuroscience, University of Virginia, Charlottesville, Virginia, USA.ORCID 0000-0002-6795-0866
William A PetriDivision of Infectious Diseases and International Health, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia, USA.ORCID 0000-0002-7268-1218
University of Virginia Health System · US

Funding

Role of Type 2 Immunity in Innate Protection from C. difficileR01AI124214 · NIAID · UNIVERSITY OF VIRGINIA · PI William A Petri · 2016 to 2026
$5.4M
Global Biothreats Training ProgramT32AI055432 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI CRISS, ALISON K, PETRI, WILLIAM A · 2003 to 2022
$4.0M
Inflammasome activation and lymphatic dysfunction in traumatic brain injuryR01NS106383 · NINDS · UNIVERSITY OF VIRGINIA · PI LUKENS, JOHN R · 2018 to 2022
$1.8M
NIAID NIH HHS R01 AI124214NIAID NIH HHS T32 AI055432NINDS NIH HHS R01 NS106383
6 · The paper itself

Abstract

SARS-CoV-2, the virus that causes coronavirus disease (COVID)-19, has become a persistent global health threat. Individuals who are symptomatic for COVID-19 frequently exhibit respiratory illness, which is often accompanied by neurological symptoms of anosmia and fatigue. Mounting clinical data also indicate that many COVID-19 patients display long-term neurological disorders postinfection such as cognitive decline, which emphasizes the need to further elucidate the effects of COVID-19 on the central nervous system. In this review article, we summarize an emerging body of literature describing the impact of SARS-CoV-2 infection on central nervous system (CNS) health and highlight important areas of future investigation.

Indexed as

COVID-19Nervous System DiseasesCentral Nervous SystemHumansSARS-CoV-2anosmiaCOVID-19NeuroCOVIDneuroimmunologyneuroinflammationolfactory systemSARS-CoV-2

Identifiers

PMID35770683
PMCPMC9350403
OpenAlexW4283732338

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.