Evidence mapPaperPMID 35773443Full record

Trial reportPrevention science : the official journal of the Society for Prevention Research2022

The 6-Month Efficacy of an Intensive Lifestyle Modification Program on Type 2 Diabetes Risk Among Rural Women with Prior Gestational Diabetes Mellitus: a Cluster Randomized Controlled Trial.

Yao Chen, Qinyi Zhong, Jiaxin Luo, Yujia Tang, Mingshu Li, Qian Lin, James Allen Willey, Jyu-Lin Chen, Robin Whittemore, Jia Guo

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Prevention science : the official journal of the Society for Prevention Research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Meta-Analysis of the Effect of Nursing Intervention on Children with Type 2 Diabetes.Computational and mathematical methods in medicine · 2022
    Pooled it
  4. Trial
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Yao Chen *Xiangya School of Nursing, Central South University, 172 Tongzipo Road, Changsha, 410013, Hunan, China.
Qinyi Zhong *Xiangya School of Nursing, Central South University, 172 Tongzipo Road, Changsha, 410013, Hunan, China.
Jiaxin LuoXiangya School of Nursing, Central South University, 172 Tongzipo Road, Changsha, 410013, Hunan, China.
Yujia TangXiangya School of Nursing, Central South University, 172 Tongzipo Road, Changsha, 410013, Hunan, China.
Mingshu LiXiangya School of Public Health, Central South University, Changsha, 410078, Hinan, China.
Qian LinXiangya School of Public Health, Central South University, Changsha, 410078, Hinan, China.
James Allen WilleyPhilip R. Lee Institute for Health Policy Research, University of California, San Francisco, San Francisco, CA, 94118, USA.
Jyu-Lin ChenSchool of Nursing, University of California, San Francisco, San Francisco, CA, 94118, USA.
Robin WhittemoreSchool of Nursing, Yale University, New Haven, CT, 06520, USA.
Jia GuoXiangya School of Nursing, Central South University, 172 Tongzipo Road, Changsha, 410013, Hunan, China. guojia621@163.com.ORCID 0000-0002-8304-9947
Central South University · CNUniversity of California, San Francisco · USYale University · US

Funding

Yale Clinical and Translational Science AwardUL1TR001863 · YALE UNIVERSITY · 2025 to 2025
$9.9M
PILOT &FEASIBILTY 2P30DK063720 · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · 2003 to 2005
$3.6M
New York Regional Center for Diabetes Translation ResearchP30DK111022 · ALBERT EINSTEIN COLLEGE OF MEDICINE · 2025 to 2025
$810k
NCATS NIH HHS UL1 TR001863NIDDK NIH HHS P30 DK063720NIDDK NIH HHS P30 DK111022
6 · The paper itself

Abstract

This study aimed to evaluate the efficacy of an intensive lifestyle modification program tailored to rural Chinese women with prior gestational diabetes mellitus compared with usual care. In a cluster randomized controlled trial, 16 towns (clusters) in two distinct rural areas in China were randomly selected (8 towns per district); and 320 women with prior gestational diabetes mellitus were recruited from these towns. With stratification for the two study districts, eight towns (160 women) were randomly assigned to the intervention group of a tailored intensive lifestyle modification program and 8 towns (160 women) to the control group. Process measures were collected on attendance, engagement, fidelity, and satisfaction. Primary efficacy outcomes included glycemic and weight-related outcomes, while secondary efficacy outcomes were behavioral outcomes and type 2 diabetes risk score, which were collected at baseline, 3-month, and 6-month follow-up. Generalized estimation equations were used to analyze the data. High attendance (72% of sessions), engagement (67% of interactive activities and group discussions), fidelity (98%), and satisfaction (92%) with the tailored intensive lifestyle modification program were achieved. There were significant reductions in fasting blood glucose, oral glucose tolerance test 2 h, waist circumference, and type 2 diabetes risk score of participants in the intervention group compared to the control group (p < .05). There was no significant intervention effect on body mass index or behavioral outcomes (p > .05). In this study, we demonstrate the successful efficacy of an Intensive Lifestyle Modification Program in reducing type 2 diabetes risk among younger women with prior gestational diabetes mellitus. This tailored program delivered by local healthcare providers is a promising approach for diabetes prevention in rural China, reducing health disparities in rural communities about diabetes prevention. Registered in the Chinese Clinical Trial Registry (ChiCTR2000037956) on 3rd Jan 2018.

Indexed as

Diabetes, GestationalDiabetes Mellitus, Type 2Blood GlucoseFemaleHumansLife StylePregnancyRural PopulationBlood GlucoseGestational diabetesLess-developed areaPreventionRandomized controlled trialType 2 diabetes mellitusWoman

Identifiers

PMID35773443
PMCPMC9489585
OpenAlexW4283750628

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.