Evidence mapPaperPMID 35773564Full record

ReviewCurrent atherosclerosis reports2022

Biology, Bias, or Both? The Contribution of Sex and Gender to the Disparity in Cardiovascular Outcomes Between Women and Men.

Sarah Gauci, Susie Cartledge, Julie Redfern, Robyn Gallagher, Rachel Huxley, Crystal Man Ying Lee, Amy Vassallo, Adrienne O'Neil

Abstract readReview
In one paragraph

Review in Current atherosclerosis reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 3 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Atherosclerosis after pre-eclampsia: systematic review and meta-analysis.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2026
    Pooled it
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  15. Mitochondria, Sex, and Cardiovascular Disease: A Complex Interplay.International journal of molecular sciences · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sarah GauciInstitute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong, VIC, Australia. sarah.gauci@deakin.edu.au.ORCID 0000-0002-1907-1066
Susie CartledgeSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
Julie RedfernSchool of Health Sciences, University of Sydney, Sydney, NSW, Australia.
Robyn GallagherSusan Wakil School of Nursing and Midwifery, University of Sydney, Sydney, NSW, Australia.
Rachel HuxleyFaculty of Health, Deakin University, Melbourne, VIC, Australia.
Crystal Man Ying LeeSchool of Population Health, Curtin University, Perth, WA, Australia.
Amy VassalloThe George Institute for Global Health, University of New South Wales, Sydney, NSW, Australia.
Adrienne O'NeilInstitute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong, VIC, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewCardiovascular disease (CVD) is the leading cause of mortality and morbidity worldwide for both men and women. However, CVD is understudied, underdiagnosed, and undertreated in women. This bias has resulted in women being disproportionately affected by CVD when compared to men. The aim of this narrative review is to explore the contribution of sex and gender on CVD outcomes in men and women and offer recommendations for researchers and clinicians. RECENT

findingsEvidence demonstrates that there are sex differences (e.g., menopause and pregnancy complications) and gender differences (e.g., socialization of gender) that contribute to the inequality in risk, presentation, and treatment of CVD in women. To start addressing the CVD issues that disproportionately impact women, it is essential that these sex and gender differences are addressed through educating health care professionals on gender bias; offering patient-centered care and programs tailored to women's needs; and conducting inclusive health research.

Indexed as

Cardiovascular DiseasesSexismBiologyFemaleHumansMaleMenopausePregnancyRisk FactorsSex FactorsCardiovascular diseaseGenderSexWomen

Identifiers

PMID35773564
PMCPMC9399064

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.