ArticleEvidence-based complementary and alternative medicine : eCAM2022
Evaluation of Antidiabetic and Antihyperlipidemic Activity of 80% Methanolic Extract of the Root of
Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 10 citations in OpenAlex.
- Targeting Hypoglycemic Natural Products from the Cloud Forest Plants Using Chemotaxonomic Computer-Assisted Selection.International journal of molecular sciences · 2024Article
- Evaluation of antioxidant and antihyperglycemic effectsMetabolism open · 2024Article
- A comprehensiveFrontiers in pharmacology · 2024Review
- In Vitro, In Silico, and In Vivo Studies ofACS omega · 2023Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Conventional antidiabetic drugs are linked with a number of contraindications and untoward effects. The root decoction of Methods: Using normoglycemic, oral glucose-loaded, and streptozotocin-induced diabetic mice models, the hypoglycemic and antihyperglycemic activities of 80% methanolic root extract were investigated. On streptozotocin-induced diabetic mice, the effect of the test extract on diabetic lipid profile and body weight was also investigated. Further, the in vitro Results: The test extract was safe at a limit test dose of 2 g/kg. Dose-dependent Conclusion: The study revealed that the test extract showed promising antihyperglycemic and antihyperlipidemic activity. Thus, the findings back up its use in Ethiopian remedies for diabetes.
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Registered trials
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