Evidence map›Paper›PMID 35776546›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Distinct gene expression dynamics in developing and regenerating crustacean limbs.

Chiara Sinigaglia, Alba Almazán, Marie Lebel, Marie Sémon, Benjamin Gillet, Sandrine Hughes, Eric Edsinger, Michalis Averof, Mathilde Paris

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
8.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 55 citations in OpenAlex.

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  13. Transcriptomic Analysis across Crayfish (International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Chiara SinigagliaInstitut de Génomique Fonctionnelle de Lyon, CNRS, École Normale Supérieure de Lyon, and Université Claude Bernard Lyon-1, Lyon 69007, France.ORCID 0000-0002-7195-7091
Alba AlmazánInstitut de Génomique Fonctionnelle de Lyon, CNRS, École Normale Supérieure de Lyon, and Université Claude Bernard Lyon-1, Lyon 69007, France.ORCID 0000-0001-9933-4278
Marie LebelInstitut de Génomique Fonctionnelle de Lyon, CNRS, École Normale Supérieure de Lyon, and Université Claude Bernard Lyon-1, Lyon 69007, France.ORCID 0000-0003-0150-0384
Marie SémonLaboratoire de Biologie et Modélisation de la Cellule, École Normale Supérieure de Lyon, 69364 Lyon, France.
Benjamin GilletInstitut de Génomique Fonctionnelle de Lyon, CNRS, École Normale Supérieure de Lyon, and Université Claude Bernard Lyon-1, Lyon 69007, France.ORCID 0000-0002-6610-4537
Sandrine HughesInstitut de Génomique Fonctionnelle de Lyon, CNRS, École Normale Supérieure de Lyon, and Université Claude Bernard Lyon-1, Lyon 69007, France.ORCID 0000-0003-3932-9180
Eric EdsingerMolecular Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037.ORCID 0000-0002-1012-1506
Michalis AverofInstitut de Génomique Fonctionnelle de Lyon, CNRS, École Normale Supérieure de Lyon, and Université Claude Bernard Lyon-1, Lyon 69007, France.ORCID 0000-0002-6803-7251
Mathilde ParisInstitut de Génomique Fonctionnelle de Lyon, CNRS, École Normale Supérieure de Lyon, and Université Claude Bernard Lyon-1, Lyon 69007, France.ORCID 0000-0001-6166-6672
Université Claude Bernard Lyon 1 · FRÉcole Normale Supérieure de Lyon · FRSalk Institute for Biological Studies · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regenerating animals have the ability to reproduce body parts that were originally made in the embryo and subsequently lost due to injury. Understanding whether regeneration mirrors development is an open question in most regenerative species. Here, we take a transcriptomics approach to examine whether leg regeneration shows similar temporal patterns of gene expression as leg development in the embryo, in the crustacean

Indexed as

AmphipodaExtremitiesRegenerationAnimalsEmbryo, NonmammalianGene Expressioncrustaceanleg developmentParhyale hawaiensisregenerationtranscriptional profiling

Identifiers

PMID35776546
PMCPMC9271199
OpenAlexW4283751230

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.