Evidence map›Paper›PMID 35778658›Full record

ArticleBiometals : an international journal on the role of metal ions in biology, biochemistry, and medicine2022

Heteroleptic oxidovanadium(IV)-malate complex improves glucose uptake in HepG2 and enhances insulin action in streptozotocin-induced diabetic rats.

Thanise Pitelli de Nigro, Graciele Cristiane More Manica, Susan Webber de Souza, Carlos Henrique Alves Jesus, Rúbia Camila Ronqui Bottini, Juliana Morais Missina, Glaucio Valdameri, Giovana Gioppo Nunes, Joice Maria da Cunha, Geraldo Picheth and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 62% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Thanise Pitelli de NigroPrograma de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
Graciele Cristiane More ManicaPrograma de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
Susan Webber de SouzaPrograma de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
Carlos Henrique Alves JesusPrograma de Pós-Graduação em Farmacologia, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
Rúbia Camila Ronqui BottiniDepartamento de Química, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
Juliana Morais MissinaDepartamento de Química, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
Glaucio ValdameriPrograma de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
Giovana Gioppo NunesDepartamento de Química, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
Joice Maria da CunhaPrograma de Pós-Graduação em Farmacologia, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
Geraldo PichethPrograma de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
Fabiane Gomes de Moraes RegoPrograma de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Paraná, Curitiba, Paraná, Brazil. rego@ufpr.br.ORCID 0000-0003-1726-8524
Universidade Federal do Paraná · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus, a complex and heterogeneous disease associated with hyperglycemia, is a leading cause of mortality and reduces life expectancy. Vanadium complexes have been studied for the treatment of diabetes. The effect of complex [VO(bpy)(mal)]·H

Indexed as

Diabetes Mellitus, ExperimentalAnimalsBlood GlucoseHumansHypoglycemic AgentsInsulinMalatesMaleRatsRats, WistarStreptozocinVanadatesVanadiumBlood GlucoseHypoglycemic AgentsInsulinMalatesmalic acidStreptozocinVanadatesVanadiumAntidiabetic effectDiabetes mellitusGlucose uptakeOxidovanadium(IV) complexSTZ-induced diabetic ratsVanadium

Identifiers

PMID35778658
OpenAlexW4283768281

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.