Evidence map›Paper›PMID 35779163›Full record

ArticlePurinergic signalling2022

Lysophosphatidylcholine induces adenosine release from macrophages via TRPM7-mediated mitochondrial activation.

Ahmed M Youssef, Dong-Keun Song

RetractedOpen access · greenAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Purinergic signalling, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ahmed M YoussefDepartment of Pharmacology, College of Medicine, Hallym University, Chuncheon, Gangwon-do, 24252, Republic of Korea.
Dong-Keun SongDepartment of Pharmacology, College of Medicine, Hallym University, Chuncheon, Gangwon-do, 24252, Republic of Korea. dksong@hallym.ac.kr.
Hallym University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Even though macrophages have the potential to harm tissues through excessive release of inflammatory mediators, they play protective roles to maintain tissue integrity. In this study, we hypothesized that lysophosphatidylcholine (LPC), via G2A and A

Indexed as

AdenosineLysophosphatidylcholinesMacrophagesTRPM Cation ChannelsAdenosine TriphosphateCyclic AMP-Dependent Protein KinasesHypoxiaMagnesiumNetrin-1Protein Serine-Threonine KinasesAdenosineAdenosine TriphosphateCyclic AMP-Dependent Protein KinasesLysophosphatidylcholinesMagnesiumNetrin-1Protein Serine-Threonine KinasesTRPM Cation ChannelsAdenosine releaseBone marrow-derived macrophagesIntracellular magnesiumLipopolysaccharideLysophosphatidylcholineTRPM7

Identifiers

PMID35779163
PMCPMC9391566
OpenAlexW4283770728

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.