Evidence map›Paper›PMID 35780862›Full record

ArticleJournal of molecular and cellular cardiology2022

Characterization of decellularized left and right ventricular myocardial matrix hydrogels and their effects on cardiac progenitor cells.

Jervaughn D Hunter, Arielle Hancko, Preety Shakya, Ryan Hill, Anthony J Saviola, Kirk C Hansen, Michael E Davis, Karen L Christman

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of molecular and cellular cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Stress relaxation rates of myocardium from failing and non-failing hearts.Biomechanics and modeling in mechanobiology · 2025
    Article
  4. Paintable Decellularized-ECM Hydrogel for Preventing Cardiac Tissue Damage.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jervaughn D HunterDepartment of Bioengineering, Sanford Consortium for Regenerative Medicine, UC San Diego, USA.
Arielle HanckoDepartment of Bioengineering, Sanford Consortium for Regenerative Medicine, UC San Diego, USA.
Preety ShakyaWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Emory University, USA.
Ryan HillDepartment of Biochemistry and Molecular Genetics, Anschutz Medical Campus, University of Colorado, Aurora, CO, USA.
Anthony J SaviolaDepartment of Biochemistry and Molecular Genetics, Anschutz Medical Campus, University of Colorado, Aurora, CO, USA.
Kirk C HansenDepartment of Biochemistry and Molecular Genetics, Anschutz Medical Campus, University of Colorado, Aurora, CO, USA.
Michael E DavisWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Emory University, USA.
Karen L ChristmanDepartment of Bioengineering, Sanford Consortium for Regenerative Medicine, UC San Diego, USA. Electronic address: christman@eng.ucsd.edu.
University of Colorado Anschutz Medical Campus · USThe Wallace H. Coulter Department of Biomedical Engineering · USUniversity of California, San Diego · USSanford Consortium for Regenerative Medicine · US

Funding

Role of Complement-Driven Pulmonary Vascular Inflammation in PHP01HL152961 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI TUDER, RUBIN M. · 2020 to 2024
$14.1M
Integrative Bioengineering of Heart, Vessels, and BloodT32HL105373 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHIEN, SHU, INTAGLIETTA, MARCOS · 2010 to 2019
$3.6M
Injectable Biomaterial for Treating Hypoplastic Left Heart SyndromeR01HL146147 · NHLBI · EMORY UNIVERSITY · PI CHRISTMAN, KAREN L, DAVIS, MICHAEL E · 2019 to 2022
$2.8M
Quadrupole-Orbitrap Mass SpectrometerS10OD021641 · OD · UNIVERSITY OF COLORADO DENVER · PI HANSEN, KIRK C · 2017 to 2017
$600k
Investigation of a Right Ventricle Based Decellularized Extracellular Matrix Hydrogel and Cardiac Progenitor Cells as a Treatment for Right Ventricular Heart FailureF31HL158212 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HUNTER, JERVAUGHN D · 2022 to 2023
$63k
NHLBI NIH HHS F31 HL158212NHLBI NIH HHS P01 HL152961NHLBI NIH HHS R01 HL146147NHLBI NIH HHS T32 HL105373NIH HHS S10 OD021641
6 · The paper itself

Abstract

Congenital heart defects are the leading cause of right heart failure in pediatric patients. Implantation of c-kit

Indexed as

Heart FailureHydrogelsAnimalsBiocompatible MaterialsCollagenExtracellular MatrixHeart VentriclesMyocardiumReactive Oxygen SpeciesStem CellsSwineBiocompatible MaterialsCollagenHydrogelsReactive Oxygen Speciesbiomaterialcardiac progenitor cellsextracellular matrixhydrogelleft ventricleRight ventricle

Identifiers

PMID35780862
PMCPMC11091826
OpenAlexW4283744530

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.