Evidence map›Paper›PMID 35787805›Full record

ArticleBMC medical informatics and decision making2022

Classification of multi-differentiated liver cancer pathological images based on deep learning attention mechanism.

Chen Chen, Cheng Chen, Mingrui Ma, Xiaojian Ma, Xiaoyi Lv, Xiaogang Dong, Ziwei Yan, Min Zhu, Jiajia Chen

Open access · goldAbstract read
In one paragraph

Article in BMC medical informatics and decision making, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 46 citations in OpenAlex.

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  15. SMiT: symmetric mask transformer for disease severity detection.Journal of cancer research and clinical oncology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Chen Chen *College of Information Science and Engineering, Xinjiang University, Northwest Road, Shayibake District, Urumqi, 830046, Xinjiang, China.
Cheng Chen *College of Information Science and Engineering, Xinjiang University, Northwest Road, Shayibake District, Urumqi, 830046, Xinjiang, China.
Mingrui MaXinjiang Medical University Cancer Hospital, Suzhou East Road, Xinshi District, Urumqi, 830011, Xinjiang, China.
Xiaojian MaXinjiang Medical University Cancer Hospital, Suzhou East Road, Xinshi District, Urumqi, 830011, Xinjiang, China.
Xiaoyi LvCollege of Information Science and Engineering, Xinjiang University, Northwest Road, Shayibake District, Urumqi, 830046, Xinjiang, China. xiaoz813@163.com.
Xiaogang DongXinjiang Medical University Cancer Hospital, Suzhou East Road, Xinshi District, Urumqi, 830011, Xinjiang, China. 11418267@zju.edu.cn.
Ziwei YanCollege of Information Science and Engineering, Xinjiang University, Northwest Road, Shayibake District, Urumqi, 830046, Xinjiang, China.
Min ZhuDepartment of Pathology, Karamay Central Hospital of XinJiang Karamay, Karamay, 834000, Xinjiang Uygur Autonomous Region, China.
Jiajia ChenChangji Vocational and Technical College, Urumqi, 830011, China.
Xinjiang University · CNXinjiang Medical University · CNKaramay Central Hospital of Xinjiang · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLiver cancer is one of the most common malignant tumors in the world, ranking fifth in malignant tumors. The degree of differentiation can reflect the degree of malignancy. The degree of malignancy of liver cancer can be divided into three types: poorly differentiated, moderately differentiated, and well differentiated. Diagnosis and treatment of different levels of differentiation are crucial to the survival rate and survival time of patients. As the gold standard for liver cancer diagnosis, histopathological images can accurately distinguish liver cancers of different levels of differentiation. Therefore, the study of intelligent classification of histopathological images is of great significance to patients with liver cancer. At present, the classification of histopathological images of liver cancer with different degrees of differentiation has disadvantages such as time-consuming, labor-intensive, and large manual investment. In this context, the importance of intelligent classification of histopathological images is obvious.

methodsBased on the development of a complete data acquisition scheme, this paper applies the SENet deep learning model to the intelligent classification of all types of differentiated liver cancer histopathological images for the first time, and compares it with the four deep learning models of VGG16, ResNet50, ResNet_CBAM, and SKNet. The evaluation indexes adopted in this paper include confusion matrix, Precision, recall, F1 Score, etc. These evaluation indexes can be used to evaluate the model in a very comprehensive and accurate way.

resultsFive different deep learning classification models are applied to collect the data set and evaluate model. The experimental results show that the SENet model has achieved the best classification effect with an accuracy of 95.27%. The model also has good reliability and generalization ability. The experiment proves that the SENet deep learning model has a good application prospect in the intelligent classification of histopathological images.

conclusionsThis study also proves that deep learning has great application value in solving the time-consuming and laborious problems existing in traditional manual film reading, and it has certain practical significance for the intelligent classification research of other cancer histopathological images.

Indexed as

Deep LearningLiver NeoplasmsHumansReproducibility of ResultsDegree of differentiation of the whole typeHistopathological images of liver cancerIntelligent classificationSENet

Identifiers

PMID35787805
PMCPMC9254605
OpenAlexW4283806161

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.