Evidence map›Paper›PMID 35790502›Full record

SynthesisJournal of diabetes2022

Global prevalence of prediabetes in children and adolescents: A systematic review and meta-analysis.

Chengyi Han, Qing Song, Yongcheng Ren, Xinyu Chen, Xuesong Jiang, Dongsheng Hu

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of diabetes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Chengyi HanThe First Affiliated Hospital of Henan University of CM, Zhengzhou, Henan, China.
Qing SongThe First Affiliated Hospital of Henan University of CM, Zhengzhou, Henan, China.
Yongcheng RenThe Medical Collage of Huanghuai University, Zhumadian, Henan, China.
Xinyu ChenSchool of Public Health, Southwest Medical University, Chengdu, Sichuan, China.
Xuesong JiangThe First Affiliated Hospital of Henan University of CM, Zhengzhou, Henan, China.ORCID https://orcid.org/0000-0002-1724-5018
Dongsheng HuSchool of Public Health, Shenzhen University Health Science Center, Shenzhen, Guangdong, China.ORCID https://orcid.org/0000-0002-9998-8041
First Affiliated Hospital of Henan University of Traditional Chinese Medicine · CNHuanghuai University · CNShenzhen University Health Science Center · CNSouthwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrediabetes is a pivotal risk factor for developing diabetes. This meta-analysis was performed to assess the global prevalence of childhood prediabetes.

methodsA systematic search was conducted for studies of prediabetes prevalence in the general pediatric population from inception until December 2021. Random-effects meta-analysis was used to combine the data. Variations in the prevalence estimates in different subgroups (age group, sex, setting, investigation period, body mass index [BMI] group, family history of diabetes, diagnosis criteria, World Health Organization [WHO] and World Bank [WB] regions) were examined by subgroup meta-analysis.

resultsA total of 48 studies were included in the meta-analysis. The pooled prevalence was 8.84% (95% CI, 6.74%-10.95%) for prediabetes in childhood. Subgroup meta-analyses showed that the prevalence was higher in males than females (8.98% vs 8.74%, P < .01), in older compared to younger children (7.56% vs. 2.51%, p < 0.01), in urban compared to rural areas (6.78% vs. 2.47, p < 0.01), and higher in children with a family history of diabetes than in those without such a history (7.59% vs. 6.80%, p < 0.01). We observed an upward trend in prediabetes prevalence from 0.93% to 10.66% over past decades (p < 0.01). The pooled prevalence increased from 7.64% to 14.27% with increased BMI (p < 0.01). Pooled prevalence was the lowest for criterion A among different diagnosis criteria (p < 0.01). For WHO and WB regions, the European Region and high-income countries yielded the lowest pooled prevalence (p < 0.01).

conclusionsElevated prediabetes prevalence in childhood reaches an alarming level. Intensive lifestyle modification is needed to improve the prediabetes epidemic.

Indexed as

Diabetes Mellitus, Type 2Prediabetic StateAdolescentAgedBody Mass IndexChildFemaleHumansMalePrevalenceRisk Factorsadolescentmeta-analysisprediabetesprevalencesystematic review前期糖尿病患病率系统回顾荟萃分析青少年

Identifiers

PMID35790502
PMCPMC9310043
OpenAlexW4284678968

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.