Evidence map›Paper›PMID 35790771›Full record

ArticleNature communications2022

Single-cell RNA-sequencing analysis of the developing mouse inner ear identifies molecular logic of auditory neuron diversification.

Charles Petitpré, Louis Faure, Phoebe Uhl, Paula Fontanet, Iva Filova, Gabriela Pavlinkova, Igor Adameyko, Saida Hadjab, Francois Lallemend

Abstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed.

  1. Article
  2. Article
  3. Functionalized Biomimetic Scaffolds for Human-Derived Auditory Neural Circuit Construction.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  4. Spontaneous Calcium Signalling in the Developing Mammalian Cochlea.Journal of the Association for Research in Otolaryngology : JARO · 2026
    Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. SHANK2 establishes auditory hair bundle architecture essential for mammalian hearing.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Charles Petitpré *Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Louis Faure *Department of Neuroimmunology, Center for Brain Research, Medical University Vienna, 1090, Vienna, Austria.ORCID 0000-0003-4621-586X
Phoebe UhlDepartment of Neuroscience, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-5521-7261
Paula FontanetDepartment of Neuroscience, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-5324-6077
Iva FilovaInstitute of Biotechnology CAS, 25250, Vestec, Czech Republic.
Gabriela PavlinkovaInstitute of Biotechnology CAS, 25250, Vestec, Czech Republic.
Igor AdameykoDepartment of Neuroimmunology, Center for Brain Research, Medical University Vienna, 1090, Vienna, Austria.ORCID 0000-0001-5471-0356
Saida HadjabDepartment of Neuroscience, Karolinska Institutet, Stockholm, Sweden. saida.hadjab@ki.se.ORCID 0000-0001-7953-8396
Francois LallemendDepartment of Neuroscience, Karolinska Institutet, Stockholm, Sweden. francois.lallemend@ki.se.ORCID 0000-0001-5484-0011

Funding

Austrian Science Fund FWF DOC 33
6 · The paper itself

Abstract

Different types of spiral ganglion neurons (SGNs) are essential for auditory perception by transmitting complex auditory information from hair cells (HCs) to the brain. Here, we use deep, single cell transcriptomics to study the molecular mechanisms that govern their identity and organization in mice. We identify a core set of temporally patterned genes and gene regulatory networks that may contribute to the diversification of SGNs through sequential binary decisions and demonstrate a role for NEUROD1 in driving specification of a I

Indexed as

NeuronsSpiral GanglionAnimalsCell DifferentiationHair Cells, AuditoryMiceRNARNA

Identifiers

PMID35790771
PMCPMC9256748

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.