Evidence map›Paper›PMID 35794776›Full record

ReviewCurrent neuropharmacology2023

Epilepsy and Cognitive Impairment in Childhood and Adolescence: A Mini-Review.

Francesca Felicia Operto, Grazia Maria Giovanna Pastorino, Andrea Viggiano, Giovanni Battista Dell'Isola, Gianluca Dini, Alberto Verrotti, Giangennaro Coppola

Open access · greenAbstract readReview
In one paragraph

Review in Current neuropharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 53 citations in OpenAlex.

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  20. Correlation Between Liver Function and Risk of Post-Stroke Epilepsy.Journal of multidisciplinary healthcare · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Francesca Felicia OpertoChild and Adolescent Neuropsychiatry Unit, Department of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, SA, Italy.
Grazia Maria Giovanna PastorinoChild and Adolescent Neuropsychiatry Unit, Department of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, SA, Italy.
Andrea ViggianoDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Baronissi, SA, Italy.
Giovanni Battista Dell'IsolaDepartment of Pediatrics, University of Perugia, Giorgio Menghini Square, 06129 Perugia, Italy.
Gianluca DiniDepartment of Pediatrics, University of Perugia, Giorgio Menghini Square, 06129 Perugia, Italy.
Alberto VerrottiDepartment of Pediatrics, University of Perugia, Giorgio Menghini Square, 06129 Perugia, Italy.
Giangennaro CoppolaChild and Adolescent Neuropsychiatry Unit, Department of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, SA, Italy.
University of Salerno · ITUniversity of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Managing epilepsy in people with an intellectual disability remains a therapeutic challenge and must take into account additional issues such as diagnostic difficulties and frequent drug resistance. Advances in genomic technologies improved our understanding of epilepsy and raised the possibility to develop patients-tailored treatments acting on the key molecular mechanisms involved in the development of the disease. In addition to conventional antiseizure medications (ASMs), ketogenic diet, hormone therapy and epilepsy surgery play an important role, especially in cases of drugresistance. This review aims to provide a comprehensive overview of the mainfactors influencing cognition in children and adolescents with epilepsy and the main therapeutic options available for the epilepsies associated with intellectual disability.

Indexed as

Cognitive DysfunctionDiet, KetogenicEpilepsyIntellectual DisabilityAdolescentChildCognitionHumansanti-seizure medicationcognitive impairmentEpilepsyganaxolonegene therapyintellectual disabilityketogenic diet

Identifiers

PMID35794776
PMCPMC10514538
OpenAlexW4284698589

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.