Evidence map›Paper›PMID 35794851›Full record

ArticleAge and ageing2022

Provision of a comprehensive medicines review is associated with lower mortality risk for residents of aged care facilities: a retrospective cohort study.

Janet K Sluggett, Gillian E Caughey, Tracy Air, Max Moldovan, Catherine Lang, Grant Martin, Stephen R Carter, Shane Jackson, Andrew C Stafford, Steve L Wesselingh and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Age and ageing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Janet K SluggettUniSA Allied Health and Human Performance, University of South Australia, Adelaide, South Australia, Australia.ORCID 0000-0002-9059-5209
Gillian E CaugheyUniSA Allied Health and Human Performance, University of South Australia, Adelaide, South Australia, Australia.ORCID 0000-0003-1192-4121
Tracy AirRegistry of Senior Australians, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
Max MoldovanRegistry of Senior Australians, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
Catherine LangRegistry of Senior Australians, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
Grant MartinAustralian Association of Consultant Pharmacy, Fyshwick, Australian Capital Territory, Australia.
Stephen R CarterSchool of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
Shane JacksonSchool of Pharmacy and Pharmacology, University of Tasmania, Hobart, Tasmania, Australia.
Andrew C StaffordCurtin Medical School, Faculty of Health Sciences, Curtin University, Perth, Western Australia, Australia.
Steve L WesselinghRegistry of Senior Australians, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
Maria C InacioUniSA Allied Health and Human Performance, University of South Australia, Adelaide, South Australia, Australia.
South Australian Health and Medical Research Institute · AUUniversity of South Australia · AUAustralian Association of Gerontology · AUCurtin University · AUThe University of Sydney · AUUniversity of Tasmania · AUUniversity of Technology Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundno studies have examined the impact of residential medication management review (RMMR, a 24-year government subsidised comprehensive medicines review program) in Australian residential aged care facilities (RACFs) on hospitalisation or mortality.

objectiveto examine associations between RMMR provision in the 6-12 months after RACF entry and the 12-month risk of hospitalisation and mortality among older Australians in RACFs.

designretrospective cohort study. SUBJECTS: individuals aged 65-105 years taking at least one medicine, who entered an RACF in three Australian states between 1 January 2012 and 31 December 2015 and spent at least 6 months in the RACF (n = 57,719).

methodsCox regression models estimated adjusted hazard ratios (aHRs) with 95% confidence intervals (CIs) for associations between RMMR provision and mortality. Adjusted subdistribution hazard ratios were estimated for associations between RMMR provision and next (i) emergency department (ED) presentation or unplanned hospitalisation or (ii) fall-related ED presentation or hospitalisation.

resultsthere were 12,603 (21.8%) individuals who received an RMMR within 6-12 months of RACF entry, of whom 22.2% (95%CI 21.4-22.9) died during follow-up, compared with 23.3% (95%CI 22.9-23.7) of unexposed individuals. RMMR provision was associated with a lower risk of death due to any cause over 12-months (aHR 0.96, 95%CI 0.91-0.99), but was not associated with ED presentations or hospitalisations for unplanned events or falls.

conclusionsprovision of an RMMR in the 6-12 months after RACF entry is associated with a 4.4% lower mortality risk over 12-months but was not associated with changes in hospitalisations for unplanned events or falls.

Indexed as

Homes for the AgedHospitalizationAccidental FallsAgedAustraliaHumansRetrospective StudiesagedAustraliahomes for the agedhospitalisationlong-term careMedication reviewmedication therapy managementmortalitynursing homesolder peoplepharmaceutical servicespharmacistsresidential aged careresidential facilitiestreatment outcome

Identifiers

PMID35794851
PMCPMC9259960
OpenAlexW4284666844

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.