Evidence mapPaperPMID 35795149Full record

ArticleFrontiers in endocrinology2022

Prognostic Value of Triglyceride to High-Density Lipoprotein Cholesterol Ratio (TG/HDL-C) in IgA Nephropathy Patients.

Gaiqin Pei, Aiya Qin, Lingqiu Dong, Siqing Wang, Xiang Liu, Dandan Yang, Jiaxing Tan, Xiaoyuan Zhou, Yi Tang, Wei Qin

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Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gaiqin PeiWest China School of Medicine, Sichuan University, Chengdu, Sichuan, China.
Aiya QinWest China School of Medicine, Sichuan University, Chengdu, Sichuan, China.
Lingqiu DongWest China School of Medicine, Sichuan University, Chengdu, Sichuan, China.
Siqing WangWest China School of Medicine, Sichuan University, Chengdu, Sichuan, China.
Xiang LiuWest China School of Medicine, Sichuan University, Chengdu, Sichuan, China.
Dandan YangWest China School of Medicine, Sichuan University, Chengdu, Sichuan, China.
Jiaxing TanDepartment of Nephrology, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Xiaoyuan ZhouWest China School of Public Health, West China Forth Hospital of Sichuan University, Chengdu, China.
Yi TangDepartment of Nephrology, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Wei QinDepartment of Nephrology, West China Hospital of Sichuan University, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The triglycerides to high-density lipoprotein cholesterol (TG/HDL-C) ratio is an easy-to-use atherogenic and prognostic marker which has attracted increasing attention these days. However, whether TG/HDL-C correlate with outcomes in IgA nephropathy (IgAN) patients remains unknown. To clarify these issues, we conducted this study. Methods: A total of 1146 patients from West China Hospital of Sichuan University were retrospectively analysed between 2008 and 2018.The demographic, clinical and pathological data of all patients at the time of biopsy were collected. Then, patients were divided into the high TG/HDL group (TG/HDL ≥ 1.495, N=382) and the low TG/HDL group (TG/HDL-C < 1.495, N=764) based on the optimal cut-off value of the TG/HDL-C using receive operating curve. Cox proportional hazard models and Kaplan-Meier curves were used to evaluate the renal outcomes of IgAN. Results: The median age of the patients was 33 (26-42) years, and 44.5% were men. By correlation analysis, we found that the TG/HDL-C ratio was negatively correlated with the eGFR (r = 0.250, Conclusion: In this study, we addressed the importance of TG/HDL-C ratio as a predictive marker for IgAN progression.

Indexed as

Glomerulonephritis, IGAAdultBiomarkersCholesterol, HDLFemaleHumansMalePrognosisRetrospective StudiesTriglyceridesBiomarkersCholesterol, HDLTriglycerideshigh-density lipoprotein cholesterolIgA nephropathyprognosisTG/HDL-C ratiotriglyceride

Identifiers

PMID35795149
PMCPMC9251124

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.