Evidence mapPaperPMID 35798375Full record

GuidelineGut2022

British Society of Gastroenterology guidelines on the management of functional dyspepsia.

Christopher J Black, Peter A Paine, Anurag Agrawal, Imran Aziz, Maria P Eugenicos, Lesley A Houghton, Pali Hungin, Ross Overshott, Dipesh H Vasant, Sheryl Rudd and 3 more

Open access · bronzeAbstract readPractice Guideline
In one paragraph

Guideline in Gut, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 4 pooled it
31.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 4 syntheses or guidelines pooled it, 160 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Article
  8. Physical Activity as a Therapeutic Strategy for Functional Dyspepsia.Journal of neurogastroenterology and motility · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Gastric cancer secondary prevention in dyspeptic patients.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
    Article
  15. Article
  16. Article
  17. Review
  18. Acid peptic disorder compass: An Indian expert consensus on comprehensive management.World journal of gastrointestinal pharmacology and therapeutics · 2026
    Review
  19. Article
  20. Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 5 countries.

Christopher J BlackLeeds Teaching Hospitals NHS Trust, Leeds, UK.ORCID 0000-0001-5449-3603
Peter A PaineDivision of Diabetes, Endocrinology and Gastroenterology, University of Manchester, Manchester, UK.
Anurag AgrawalDoncaster and Bassetlaw Hospitals NHS Trust, Doncaster, UK.
Imran AzizAcademic Unit of Gastroenterology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.ORCID 0000-0003-3833-2302
Maria P EugenicosDepartment of Gastroenterology, University of Edinburgh, Edinburgh, UK.
Lesley A HoughtonLeeds Institute of Medical Research at St. James's, University of Leeds, Leeds, UK.ORCID 0000-0002-5351-0229
Pali HunginPrimary Care and General Practice, University of Newcastle, Newcastle, UK.
Ross OvershottGreater Manchester Mental Health NHS Foundation Trust, Manchester, UK.
Dipesh H VasantDivision of Diabetes, Endocrinology and Gastroenterology, University of Manchester, Manchester, UK.
Sheryl RuddNIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Richard C WinningNIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Maura CorsettiNIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Alexander C FordLeeds Teaching Hospitals NHS Trust, Leeds, UK alexf12399@yahoo.com.ORCID 0000-0001-6371-4359
Nottingham University Hospitals NHS Trust · GBUniversity of Leeds · GBDiabetes Australia · AUBassetlaw Hospital · GBGreater Manchester Mental Health NHS Foundation Trust · GBPrimary Health Care · QASheffield Teaching Hospitals NHS Foundation Trust · GBUniversity of Edinburgh · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Functional dyspepsia (FD) is a common disorder of gut-brain interaction, affecting approximately 7% of individuals in the community, with most patients managed in primary care. The last British Society of Gastroenterology (BSG) guideline for the management of dyspepsia was published in 1996. In the interim, substantial advances have been made in understanding the complex pathophysiology of FD, and there has been a considerable amount of new evidence published concerning its diagnosis and classification, with the advent of the Rome IV criteria, and management. The primary aim of this guideline, commissioned by the BSG, is to review and summarise the current evidence to inform and guide clinical practice, by providing a practical framework for evidence-based diagnosis and treatment of patients. The approach to investigating the patient presenting with dyspepsia is discussed, and efficacy of drugs in FD summarised based on evidence derived from a comprehensive search of the medical literature, which was used to inform an update of a series of pairwise and network meta-analyses. Specific recommendations have been made according to the Grading of Recommendations Assessment, Development and Evaluation system. These provide both the strength of the recommendations and the overall quality of evidence. Finally, in this guideline, we consider novel treatments that are in development, as well as highlighting areas of unmet need and priorities for future research.

Indexed as

DyspepsiaGastroenterologyHumansSocieties, MedicalUnited Kingdomfunctional dyspepsiameta-analysis

Identifiers

PMID35798375
PMCPMC9380508
OpenAlexW4284697679

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.