Evidence map›Paper›PMID 35799897›Full record

ArticleMaterials today. Bio2022

Electrostatically optimized adapalene-loaded emulsion for the treatment of acne vulgaris.

Yun Bae Ji, Hye Yun Lee, Soyeon Lee, Young Hun Kim, Kun Na, Jae Ho Kim, Sangdun Choi, Moon Suk Kim

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Acne vulgaris: advances in pathogenesis and prevention strategies.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Review
  3. Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yun Bae JiDepartment of Molecular Science and Technology, Ajou University, Suwon, 443-749, South Korea.
Hye Yun LeeDepartment of Molecular Science and Technology, Ajou University, Suwon, 443-749, South Korea.
Soyeon LeeDepartment of Molecular Science and Technology, Ajou University, Suwon, 443-749, South Korea.
Young Hun KimDepartment of Molecular Science and Technology, Ajou University, Suwon, 443-749, South Korea.
Kun NaDepartment of Biotechnology, The Catholic University of Korea, Bucheon, 420-743, South Korea.
Jae Ho KimDepartment of Molecular Science and Technology, Ajou University, Suwon, 443-749, South Korea.
Sangdun ChoiDepartment of Molecular Science and Technology, Ajou University, Suwon, 443-749, South Korea.
Moon Suk KimDepartment of Molecular Science and Technology, Ajou University, Suwon, 443-749, South Korea.
Ajou University · KRSuwon Research Institute · KRThe Catholic University of Korea Bucheon St. Mary's Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adapalene (AD) is an FDA-approved drug that shows good therapeutic efficacy for the treatment of acne vulgaris. However, due to its negative charge, AD cannot efficiently penetrate across the also negatively-charged skin membrane. This study is the first to assess the treatment of acne vulgaris using electrostatically optimized AD emulsions prepared using anionic AD with methoxy polyethylene glycol-

Indexed as

Acne vulgarisAdapaleneElectrostatic emulsifierElectrostatic interactionEmulsion

Identifiers

PMID35799897
PMCPMC9254491
OpenAlexW4283389662

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.