SynthesisObesity reviews : an official journal of the International Association for the Study of Obesity2022
Association between maternal adiposity measures and infant health outcomes: A systematic review and meta-analysis.
Synthesis in Obesity reviews : an official journal of the International Association for the Study of Obesity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.
- Maternal adiposity and perinatal and offspring outcomes: an umbrella review.Nature human behaviour · 2024Pooled it
- Association between maternal adiposity measures and infant health outcomes: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022Pooled it
- Trial
- Abdominal fat thickness predicts the risk of pregnancy-associated hypertension: A prospective cohort study.Asia Pacific journal of clinical nutrition · 2026Article
- Wrist circumference (WrC) in early gestation: A novel anthropometric predictor of gestational diabetes mellitus (GDM) in Asian Indian women.Journal of family medicine and primary care · 2026Article
- Association of Maternal Sociodemographic, Anthropometric, and Lifestyle Factors with Childhood Anthropometric Measures and Anxiety Symptoms: A Nationally Representative Cross-Sectional Study of Preschool-Aged Children in Greece.Diseases (Basel, Switzerland) · 2025Article
- Association Between Maternal Pre-Pregnancy Body Mass Index and Growth Delay in Korean Children Aged 18-36 Months: A Population-Based Study.Journal of personalized medicine · 2025Article
- Early Pregnancy Waist Circumference for Prediction of Fetal Macrosomia.Reproductive sciences (Thousand Oaks, Calif.) · 2025Article
- Expected and Desirable Preterm and Small Infant Growth Patterns.Advances in nutrition (Bethesda, Md.) · 2024Review
- Impact of anthro-metabolic indices and gestational weight gain on maternal and neonatal outcomes: a prospective observational study.Revista da Associacao Medica Brasileira (1992) · 2024Observational
- Study of How Adiposity in Pregnancy has an Effect on outcomeS (SHAPES): protocol for a prospective cohort study.BMJ open · 2023Article
- Prenatal weight and regional body composition trajectories and neonatal body composition: The NICHD Foetal Growth Studies.Pediatric obesity · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 6 institutions in 2 countries.
Funding
Abstract
Maternal obesity increases risks of adverse fetal and infant outcomes. Guidelines use body mass index to diagnose maternal obesity. Evidence suggests body fat distribution might better predict individual risk, but there is a lack of robust evidence during pregnancy. We explored associations between maternal adiposity and infant health. Searches included six databases, references, citations, and contacting authors. Screening and quality assessment were carried out by two authors independently. Random effects meta-analysis and narrative synthesis were conducted. We included 34 studies (n = 40,143 pregnancies). Meta-analysis showed a significant association between maternal fat-free mass and birthweight (average effect [AE] 18.07 g, 95%CI 12.75, 23.38) but not fat mass (AE 8.76 g, 95%CI -4.84, 22.36). Women with macrosomic infants had higher waist circumference than controls (mean difference 4.93 cm, 95% confidence interval [CI] 1.05, 8.82). There was no significant association between subcutaneous fat and large for gestational age (odds ratio 1.06 95% CI 0.91, 1.25). Waist-to-hip ratio, neck circumference, skinfolds, and visceral fat were significantly associated with several infant outcomes including small for gestational age, preterm delivery, neonatal morbidity, and mortality, although meta-analysis was not possible for these variables. Our findings suggest that some measures of maternal adiposity may be useful for risk prediction of infant outcomes. Individual participant data meta-analysis could overcome some limitations in our ability to pool published data.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.