Evidence map›Paper›PMID 35804591›Full record

ArticleAnimals : an open access journal from MDPI2022

Weighted Single-Step Genomic Best Linear Unbiased Prediction Method Application for Assessing Pigs on Meat Productivity and Reproduction Traits.

Artem Kabanov, Ekaterina Melnikova, Sergey Nikitin, Maria Somova, Oleg Fomenko, Valeria Volkova, Olga Kostyunina, Tatiana Karpushkina, Elena Martynova, Elena Trebunskikh

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Artem KabanovL.K. Ernst Federal Research Center for Animal Husbandry, Dubrovitzy Estate, Podolsk District, 142132 Moscow, Russia.ORCID 0000-0002-2277-0263
Ekaterina MelnikovaL.K. Ernst Federal Research Center for Animal Husbandry, Dubrovitzy Estate, Podolsk District, 142132 Moscow, Russia.ORCID 0000-0002-0885-8269
Sergey NikitinL.K. Ernst Federal Research Center for Animal Husbandry, Dubrovitzy Estate, Podolsk District, 142132 Moscow, Russia.ORCID 0000-0003-4943-0661
Maria SomovaL.K. Ernst Federal Research Center for Animal Husbandry, Dubrovitzy Estate, Podolsk District, 142132 Moscow, Russia.
Oleg FomenkoAll-Russian Dairy Research Institute, 115093 Moscow, Russia.
Valeria VolkovaL.K. Ernst Federal Research Center for Animal Husbandry, Dubrovitzy Estate, Podolsk District, 142132 Moscow, Russia.ORCID 0000-0002-2080-0182
Olga KostyuninaL.K. Ernst Federal Research Center for Animal Husbandry, Dubrovitzy Estate, Podolsk District, 142132 Moscow, Russia.ORCID 0000-0001-8206-3221
Tatiana KarpushkinaL.K. Ernst Federal Research Center for Animal Husbandry, Dubrovitzy Estate, Podolsk District, 142132 Moscow, Russia.
Elena MartynovaCenter of Life Sciences, Skolkovo Institute of Science and Technology, 143026 Moscow, Russia.
Elena TrebunskikhLLC "TOPGEN", Verkhnyaya Khava, 396110 Voronezh, Russia.

Funding

Russian Science Foundation 21-76-10038
6 · The paper itself

Abstract

Changes in the accuracy of the genomic estimates obtained by the ssGBLUP and wssGBLUP methods were evaluated using different reference groups. The weighting procedure's reasonableness of application Pwas considered to improve the accuracy of genomic predictions for meat, fattening and reproduction traits in pigs. Six reference groups were formed to assess the genomic data quantity impact on the accuracy of predicted values (groups of genotyped animals). The datasets included 62,927 records of meat and fattening productivity (fat thickness over 6-7 ribs (BF1, mm)), muscle depth (MD, mm) and precocity up to 100 kg (age, days) and 16,070 observations of reproductive qualities (the number of all born piglets (TNB) and the number of live-born piglets (NBA), according to the results of the first farrowing). The wssGBLUP method has an advantage over ssGBLUP in terms of estimation reliability. When using a small reference group, the difference in the accuracy of ssGBLUP over BLUP AM is from -1.9 to +7.3 percent points, while for wssGBLUP, the change in accuracy varies from +18.2 to +87.3 percent points. Furthermore, the superiority of the wssGBLUP is also maintained for the largest group of genotyped animals: from +4.7 to +15.9 percent points for ssGBLUP and from +21.1 to +90.5 percent points for wssGBLUP. However, for all analyzed traits, the number of markers explaining 5% of genetic variability varied from 71 to 108, and the number of such SNPs varied depending on the size of the reference group (79-88 for BF1, 72-81 for MD, 71-108 for age). The results of the genetic variation distribution have the greatest similarity between groups of about 1000 and about 1500 individuals. Thus, the size of the reference group of more than 1000 individuals gives more stable results for the estimation based on the wssGBLUP method, while using the reference group of 500 individuals can lead to distorted results of GEBV.

Indexed as

estimation reliabilitygenomic evaluationpigssingle-step GBLUPSNP effectsvalidation of genomic estimatesweighted single-step GBLUP

Identifiers

PMID35804591
PMCPMC9264777

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.