Evidence map›Paper›PMID 35805060›Full record

ArticleCancers2022

Effectiveness of Geriatric Assessment-Driven Interventions on Survival and Functional and Nutritional Status in Older Patients with Head and Neck Cancer: A Randomized Controlled Trial (EGeSOR).

Elena Paillaud, Lydia Brugel, Chloe Bertolus, Melany Baron, Emilie Bequignon, Philippe Caillet, Thomas Schouman, Jean Lacau Saint Guily, Sophie Périé, Eric Bouvard and 22 more

Abstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Practical Assessment and Management of Vulnerabilities in Older Patients Receiving Systemic Cancer Therapy: ASCO Guideline Update.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023
    Guideline
  3. Article
  4. Article
  5. Triage tools to inform the prioritisation of physical health services following a diagnosis of cancer: a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Comprehensive geriatric assessment predicts radiation-induced acute toxicity in prostate cancer patients.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Elena PaillaudIMRB, Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris-Est Créteil, F-94010 Créteil, France.ORCID 0000-0002-5579-9927
Lydia BrugelService d'ORL et Chirurgie Cervico-Faciale, Centre Hospitalier Intercommunal de Créteil, F-94010 Créteil, France.
Chloe BertolusService de Chirurgie Maxillo-Faciale, Sorbonne Université, Hôpital Pitié Salpétrière, Assistance-Publique Hôpitaux de Paris (AP-HP), F-75013 Paris, France.ORCID 0000-0002-4279-9805
Melany BaronService de Soins de Suites et de Réadaptation Gériatrique, Sorbonne Université, Hôpitaux Universitaires Pitié Salpêtrière-Charles Foix, Assistance-Publique Hôpitaux de Paris (AP-HP), F-94205 Ivry sur Seine, France.
Emilie BequignonService d'ORL et Chirurgie Cervico-Faciale, Centre Hospitalier Intercommunal de Créteil, F-94010 Créteil, France.
Philippe CailletIMRB, Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris-Est Créteil, F-94010 Créteil, France.
Thomas SchoumanService de Chirurgie Maxillo-Faciale, Sorbonne Université, Hôpital Pitié Salpétrière, Assistance-Publique Hôpitaux de Paris (AP-HP), F-75013 Paris, France.
Jean Lacau Saint GuilyDépartement d'ORL, Sorbonne Université, Hôpital Tenon, Assistance-Publique Hôpitaux de Paris (AP-HP), F-75020 Paris, France.
Sophie PériéDépartement d'ORL, Sorbonne Université, Hôpital Tenon, Assistance-Publique Hôpitaux de Paris (AP-HP), F-75020 Paris, France.
Eric BouvardService de Gériatrie, Hôpital Tenon, Assistance-Publique Hôpitaux de Paris (AP-HP), F-75020 Paris, France.
Marie LaurentIMRB, Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris-Est Créteil, F-94010 Créteil, France.
Didier SalvanService ORL et Cervico-Facial, Centre Hospitalier Sud Francilien, F-91100 Corbeil-Essonnes, France.ORCID 0000-0001-5671-0093
Laurence ChaumetteService de Court Sejour Gériatrique, Centre Hospitalier Sud Francilien, F-91100 Corbeil-Essonnes, France.
Laure de DeckerService de Gériatrie, Centre Hospitalier Universitaire de Nantes, F-44093 Nantes, France.
Benoit PiotService de Chirurgie Maxillo-Faciale et Stomatologie, Centre Hospitalier Universitaire de Nantes, F-44093 Nantes, France.
Beatrix BarryService ORL et Chirurgie Cervico-Faciale, Université de Paris, Hôpital Bichat, Assistance-Publique Hôpitaux de Paris (AP-HP), F-75018 Paris, France.
Agathe Raynaud-SimonService de Gériatrie, Université Paris Cité, Hôpital Bichat, Assistance-Publique Hôpitaux de Paris (AP-HP), F-75018 Paris, France.
Elisabeth SauvagetService ORL et Chirurgie Cervico-Faciale, Groupe Hospitalier Paris-Saint Joseph, F-75014 Paris, France.
Christine BachService d'ORL, Hôpital Foch, F-92150 Suresnes, France.
Antoine BizardUnité de Gériatrie Aigue, Hôpital Foch, F-92150 Suresnes, France.
Abderrahmane BounarUnité de Gériatrie Aigue, Centre Hospitalier Intercommunal Villeneuve-Saint-Georges, F-94190 Villeneuve-Saint-Georges, France.
Aurelien MinardService de Gériatrie, Hôpital Léopold Bellan, F-75014 Paris, France.
Bechara AzizService ORL et Chirurgie Cervico-Faciale, Centre Hospitalier Intercommunal Villeneuve-Saint-Georges, F-94190 Villeneuve-Saint-Georges, France.
Eric ChevalierService ORL et Chirurgie Cervico-Faciale, Groupement Hospitalier Intercommunal Le Raincy-Montfermeil, F-93370 Montfermeil, France.
Dominique ChevalierService ORL et Chirurgie Cervico-Faciale, Centre Hospitalier Universitaire de Lille, Hôpital Huriez, F-59000 Lille, France.
Cedric GaxatteService de Médecine Gériatrique, Centre Hospitalier Universitaire de Lille, F-59000 Lille, France.
Olivier MalardService d'ORL et de Chirurgie Cervico-Faciale, Centre Hospitalier Universitaire de Nantes, F-44093 Nantes, France.
Evelyne LiuuService de Gériatrie, Centre Hospitalier Universitaire de Poitiers, F-86021 Poitiers, France.
Sandrine LacourCentre de Recherche Clinique, Centre Hospitalier Intercommunal de Créteil, F-94010 Créteil, France.
Laetitia GregoireUnité de Recherche Clinique (URC-Mondor), Hôpital Henri-Mondor, AP-HP, F-94010 Créteil, France.
Charlotte LafontIMRB, Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris-Est Créteil, F-94010 Créteil, France.ORCID 0000-0002-5019-9914
Florence Canouï-PoitrineIMRB, Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris-Est Créteil, F-94010 Créteil, France.

Funding

Ligue Nationale contre le Cancer PACANthe French National Cancer Institute [INCa] [RAFC1202]
6 · The paper itself

Abstract

This study assesses the efficacy of Geriatric Assessment (GA)-driven interventions and follow-up on six-month mortality, functional, and nutritional status in older patients with head and neck cancer (HNC). HNC patients aged 65 years or over were included between November 2013 and September 2018 by 15 Ear, Nose, and Throat (ENT) and maxillofacial surgery departments at 13 centers in France. The study was of an open-label, multicenter, randomized, controlled, and parallel-group design, with independent outcome assessments. The patients were randomized 1:1 to benefit from GA-driven interventions and follow-up versus standard of care. The interventions consisted in a pre-therapeutic GA, a standardized geriatric intervention, and follow-up, tailored to the cancer-treatment plan for 24 months. The primary outcome was a composite criterion including six-month mortality, functional impairment (fall in the Activities of Daily Living (ADL) score ≥2), and weight loss ≥10%. Among the patients included (

Indexed as

elderlyfunctiongeriatric assessmenthead and neck cancernutritionsurvival

Identifiers

PMID35805060
PMCPMC9265581

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.