Evidence map›Paper›PMID 35806029›Full record

ArticleInternational journal of molecular sciences2022

LRF Promotes Indirectly Advantageous Chromatin Conformation via

Vasiliki Chondrou, Athanasios-Nasir Shaukat, Georgios Psarias, Katerina Athanasopoulou, Evanthia Iliopoulou, Ariadne Damanaki, Constantinos Stathopoulos, Argyro Sgourou

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Vasiliki ChondrouBiology Laboratory, School of Science and Technology, Hellenic Open University, 26335 Patras, Greece.
Athanasios-Nasir ShaukatDepartment of Biochemistry, School of Medicine, University of Patras, 26504 Patras, Greece.ORCID 0000-0003-2548-2846
Georgios PsariasBiology Laboratory, School of Science and Technology, Hellenic Open University, 26335 Patras, Greece.ORCID 0000-0002-8414-855X
Katerina AthanasopoulouBiology Laboratory, School of Science and Technology, Hellenic Open University, 26335 Patras, Greece.
Evanthia IliopoulouBiology Laboratory, School of Science and Technology, Hellenic Open University, 26335 Patras, Greece.
Ariadne DamanakiBiology Laboratory, School of Science and Technology, Hellenic Open University, 26335 Patras, Greece.
Constantinos StathopoulosDepartment of Biochemistry, School of Medicine, University of Patras, 26504 Patras, Greece.ORCID 0000-0002-5699-4118
Argyro SgourouBiology Laboratory, School of Science and Technology, Hellenic Open University, 26335 Patras, Greece.
Hellenic Open University · GRUniversity of Patras · GR

Funding

ELKE_EAP 80250European Social Fund- ESF MIS-5033021
6 · The paper itself

Abstract

The hemoglobin switch from fetal (HbF) to adult (HbA) has been studied intensively as an essential model for gene expression regulation, but also as a beneficial therapeutic approach for β-hemoglobinopathies, towards the objective of reactivating HbF. The transcription factor LRF (Leukemia/lymphoma-related), encoded from the

Indexed as

RNA, Long NoncodingTranscription FactorsAdultbeta-GlobinsCarrier ProteinsCell Line, TumorChromatinDNA-Binding ProteinsDNA, IntergenicFetal Hemoglobingamma-GlobinsHemoglobin AHumansbeta-GlobinsCarrier ProteinsChromatinDNA-Binding ProteinsDNA, IntergenicFetal Hemoglobingamma-GlobinsHemoglobin ARNA, Long NoncodingTranscription FactorsZBTB7A protein, humanBGLT3-lncRNA expressionchromatin conformationhemoglobin switchLRF/ZBTB7A overexpression

Identifiers

PMID35806029
PMCPMC9266405
OpenAlexW4283586365

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.