Evidence map›Paper›PMID 35807292›Full record

ArticleMolecules (Basel, Switzerland)2022

Naphthalene Diimides Carrying Two β-Cyclodextrins Prefer Telomere RNA G-Quadruplex Recognition.

Tingting Zou, Yuka Sato, Shuma Kaneyoshi, Kota Mano, Rui Yasukawa, Yoshifumi Nakano, Satoshi Fujii, Shinobu Sato, Shigeori Takenaka

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tingting ZouDepartment of Applied Chemistry, Kyushu Institute of Technology, Fukuoka 804-8550, Japan.
Yuka SatoDepartment of Applied Chemistry, Kyushu Institute of Technology, Fukuoka 804-8550, Japan.
Shuma KaneyoshiDepartment of Applied Chemistry, Kyushu Institute of Technology, Fukuoka 804-8550, Japan.
Kota ManoDepartment of Applied Chemistry, Kyushu Institute of Technology, Fukuoka 804-8550, Japan.ORCID 0000-0002-4364-4450
Rui YasukawaDepartment of Applied Chemistry, Kyushu Institute of Technology, Fukuoka 804-8550, Japan.
Yoshifumi NakanoDepartment of Applied Chemistry, Kyushu Institute of Technology, Fukuoka 804-8550, Japan.
Satoshi FujiiDepartment of Bioscience and Bioinformatics, Kyushu Institute of Technology, Fukuoka 820-8502, Japan.ORCID 0000-0002-3341-8644
Shinobu SatoDepartment of Applied Chemistry, Kyushu Institute of Technology, Fukuoka 804-8550, Japan.ORCID 0000-0002-3813-0535
Shigeori TakenakaDepartment of Applied Chemistry, Kyushu Institute of Technology, Fukuoka 804-8550, Japan.

Funding

Grants-in-Aid from the Ministry of Education, Culture, Sports, Science, and Technology, 19H02748Nakatani Foundation for advancement of measuring technologies in biomedical engineering S.T.
6 · The paper itself

Abstract

Newly synthesized naphthalene diimide carrying two β-cyclodextrins (NDI-β-CyDs) showed improved specificity for the parallel G-quadruplex structure alongside the hybrid G-quadruplex structure. Specifically, the highest binding affinity of NDI-β-CyDs for the telomere RNA G-quadruplex was observed. The binding simulation indicated that β-cyclodextrins might be available for loop nucleobase inclusion under its complex.

Indexed as

beta-CyclodextrinsG-QuadruplexesImidesLigandsNaphthalenesRNATelomerebeta-CyclodextrinsImidesLigandsnaphthalenediimideNaphthalenesRNAapyromidinic sitesc-kitc-mycDNAnaphthalene diimidenucleobase inclusionparallel G-quadruplexRNAtelomere RNAβ-cyclodextrins (β-CyDs)

Identifiers

PMID35807292
PMCPMC9268153

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.