ArticlePlants (Basel, Switzerland)2022
Phytochemical Analysis, Antioxidant, Antimicrobial, and Cytotoxic Activity of Different Extracts of
Article in Plants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
- Hidden diversity and chemical variation within Parmelia saxatilis group (Lecanorales, lichenized Ascomycota) and description of a new species P. tobolewskiana.Scientific reports · 2026Article
- Radioprotective potential of Ophioparma ventosa (L.) Norman extract against UV-C-induced damage in Allium cepa.Scientific reports · 2026Article
- Extraction, Characterization and Biological Activities of Selected Lichens Growing in Serbia.Journal of fungi (Basel, Switzerland) · 2026Article
- The Natural Anthraquinone Parietin InactivatesPharmaceutics · 2025Article
- Unassuming Lichens: Nature's Hidden Antimicrobial Warriors.International journal of molecular sciences · 2025Review
- An investigation on the cardioprotective potential of lichen compound protocetraric acid by HNaunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Evaluating the impact of Xanthoparmelia conspersa extracts on signaling in HeLa cells and exploring their diverse biological activities.Scientific reports · 2024Article
- Article
- Phytochemical Analysis and Antioxidant, Antimicrobial, and Antibiofilm Effects of a New Himalayan LichenInternational journal of molecular sciences · 2024Article
- Comparative Study on the Antimicrobial Activities and Metabolic Profiles of FiveJournal of fungi (Basel, Switzerland) · 2023Article
- Atranorin inhibits NLRP3 inflammasome activation by targeting ASC and protects NLRP3 inflammasome-driven diseases.Acta pharmacologica Sinica · 2023Article
- Methodological Aspects of Green Extraction of Usnic Acid Using Natural Deep Eutectic Solvents.Molecules (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
17 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to identify some of the secondary metabolites present in acetonic, methanolic, and hexanic extracts of lichen Xanthoparmelia stenophylla and to examine their antioxidant, antimicrobial, and cytotoxic activity. Compounds of the depsid structure of lecanoric acid, obtusic acid, and atranorin as well as usnic acid with a dibenzofuran structure were identified in the extracts by HPLC. The acetone extract was shown to have the highest total phenolic (167.03 ± 1.12 mg GAE/g) and total flavonoid content (178.84 ± 0.93 mg QE/g) as well as the best antioxidant activity (DPPH IC50 = 81.22 ± 0.54). However, the antimicrobial and antibiofilm tests showed the best activity of hexanic extract, especially against strains of B. cereus, B. subtilis, and S. aureus (MIC < 0.08, and 0.3125 mg/mL, respectively). Additionally, by using the MTT method, the acetonic extract was reported to exhibit a strong cytotoxic effect on the HeLa and HCT-116 cell lines, especially after 72 h (IC50 = 21.17 ± 1.85 and IC50 = 21.48 ± 3.55, respectively). The promising antioxidant, antimicrobial, and cytotoxic effects of Xanthoparmelia stenophylla extracts shown in the current study should be further investigated in vivo and under clinical conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.