Evidence map›Paper›PMID 35807749›Full record

SynthesisNutrients2022

Ultra-Processed Food Consumption and Mental Health: A Systematic Review and Meta-Analysis of Observational Studies.

Melissa M Lane, Elizabeth Gamage, Nikolaj Travica, Thusharika Dissanayaka, Deborah N Ashtree, Sarah Gauci, Mojtaba Lotfaliany, Adrienne O'Neil, Felice N Jacka, Wolfgang Marx

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06252701 (Assessing the Feasibility and Acceptability of the Reduction of Ultra-processed Foods From the Diets of a Subset of Patients With Depression - A Pilot Open Label Crossover Trial.), which is not on this map. Cited by 160 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
160citing papers in PubMed, 11 pooled it
45.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06252701 nacompletednot on this mapstarted 2024, after this paper: background citation

Assessing the Feasibility and Acceptability of the Reduction of Ultra-processed Foods From the Diets of a Subset of Patients With Depression - A Pilot Open Label Crossover Trial.

TypeinterventionalSponsorUniversity of California, San FranciscoRan2024 to 2025Enrolled20ConditionsDepression, Major Depressive Disorder, Weight Gain, ObesityArmsReduction of Ultra-processed foods
3 · Its place in the literature

Who cites it

160 citing papers in PubMed, 11 syntheses or guidelines pooled it, 248 citations in OpenAlex.

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  12. Trial
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  15. Article
  16. Ultra-processed food supply in hospitals: A cross-sectional analysis of Australian hospitals using cook fresh foodservices.Nutrition & dietetics : the journal of the Dietitians Association of Australia · 2026
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100 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Melissa M LaneFood & Mood Centre, The Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Deakin University, Geelong, VIC 3220, Australia.
Elizabeth GamageFood & Mood Centre, The Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Deakin University, Geelong, VIC 3220, Australia.
Nikolaj TravicaFood & Mood Centre, The Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Deakin University, Geelong, VIC 3220, Australia.
Thusharika DissanayakaFood & Mood Centre, The Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Deakin University, Geelong, VIC 3220, Australia.
Deborah N AshtreeFood & Mood Centre, The Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Deakin University, Geelong, VIC 3220, Australia.ORCID 0000-0003-3680-3860
Sarah GauciFood & Mood Centre, The Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Deakin University, Geelong, VIC 3220, Australia.ORCID 0000-0002-1907-1066
Mojtaba LotfalianyFood & Mood Centre, The Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Deakin University, Geelong, VIC 3220, Australia.
Adrienne O'NeilFood & Mood Centre, The Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Deakin University, Geelong, VIC 3220, Australia.
Felice N JackaFood & Mood Centre, The Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Deakin University, Geelong, VIC 3220, Australia.
Wolfgang MarxFood & Mood Centre, The Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Deakin University, Geelong, VIC 3220, Australia.ORCID 0000-0002-8556-8230
Deakin University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since previous meta-analyses, which were limited only to depression and by a small number of studies available for inclusion at the time of publication, several additional studies have been published assessing the link between ultra-processed food consumption and depression as well as other mental disorders. We aimed to build on previously conducted reviews to synthesise and meta-analyse the contemporary evidence base and clarify the associations between the consumption of ultra-processed food and mental disorders. A total of 17 observational studies were included (

Indexed as

Fast FoodsMental HealthAnxietyCross-Sectional StudiesDietHumansProspective Studiesanxietymajor depressive disordermental disordersmeta-analysisNOVAnutritional psychiatrypsychiatryultra-processed food

Identifiers

PMID35807749
PMCPMC9268228
OpenAlexW4283277309

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.