ArticleJournal of Alzheimer's disease : JAD2022
Facets of Personality and Risk of Cognitive Impairment: Longitudinal Findings in a Rural Community from Sardinia.
Article in Journal of Alzheimer's disease : JAD, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 13 citations in OpenAlex.
- Improving conscientiousness through a smartphone app and telecoaching intervention: insights from multiple sclerosis and healthy aging samples.Journal of neurology · 2025Trial
- Abnormal FDG-PET Patterns and Amyloid Positivity Predict Personality Changes in Cognitively Preserved Individuals.Brain sciences · 2026Article
- Personality traits and loneliness: An ecological momentary assessment study with self and partner ratings.Journal of research in personality · 2025Article
- Personality nuances and cognition: A multi-cohort and multi-method approach.Journal of psychiatric research · 2025Article
- Relationship between sun exposure and seasonal affective disorder symptoms in rural older people with different personalities: a cross-sectional study.BMC public health · 2024Article
- Physical, cognitive, and social activities as mediators between personality and cognition: evidence from four prospective samples.Aging & mental health · 2024Article
- Personality nuances and risk of dementia: Evidence from two longitudinal studies.Journal of psychiatric research · 2024Article
- Personality and cognitive errors in the Healthy Aging in Neighborhoods of Diversity across the Life Span study.Journal of research in personality · 2024Article
- Personality and Cognition: The Mediating Role of Inflammatory Markers.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024Article
- Association of personality facets and cognition in the Lifelines population-based cohort study.Journal of psychiatric research · 2023Article
- Changes in Personality Before and During Cognitive Impairment.Journal of the American Medical Directors Association · 2023Observational
- Five-Factor Model Personality Domains and Facets Associated with Markers of Cognitive Health.Journal of individual differences · 2023Article
Corrections and comments
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Authors and funding
15 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundFew studies have examined the associations between personality facets and dementia risk and rarely included individuals from rural settings or with low education.
objectiveTo examine the association between personality and the risk of cognitive impairment.
methodsParticipants (N = 1,668; age 50 to 94 at baseline; 56.4% women; 86.5% less than high school diploma) were from a rural region of Sardinia (Italy) who completed the Revised NEO Personality Inventory (NEO-PI-R) during the first wave (2001-2004) and the Mini-Mental State Examination (MMSE) at waves two to five (2005-2021). Cox regression was used to test personality and covariates as predictors of cognitive impairment based on MMSE education-adjusted cutoffs.
resultsDuring the up to 18-year follow-up (M = 10.38; SD = 4.76), 187 individuals (11.2%) scored as cognitively impaired. Participants with higher neuroticism (particularly the depression facet [HR = 1.22, 95% CI = 1.06-1.40]), and lower agreeableness (particularly the modesty facet [HR = 0.83, 95% CI = 0.71-0.97]) and lower conscientiousness (particularly the dutifulness facet [HR = 0.78, 95% CI = 0.67-0.92]) were at higher risk of cognitive impairment. Lower warmth ([HR = 0.75, 95% CI = 0.65-0.87], facet of extraversion) and ideas ([HR = 0.76, 95% CI = 0.65-0.89], facet of openness) were also associated with increased risk of impairment. These associations were virtually unchanged in models that accounted for other risk factors, including smoking, depression, obesity, hypertension, diabetes, and apolipoprotein E (APOE) ɛ4 carrier status. Across the five domains, sex and the APOE variant did not moderate the associations.
conclusionIn a sample with demographic characteristics underrepresented in dementia research, this study identifies personality domains and facets most relevant to the risk of cognitive impairment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.