Evidence map›Paper›PMID 35812313›Full record

ArticleFrontiers in physiology2022

Associations of Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease: An Individual-Level Meta-Analysis.

Tessa Schillemans, Vinicius Tragante, Buamina Maitusong, Bruna Gigante, Sharon Cresci, Federica Laguzzi, Max Vikström, Mark Richards, Anna Pilbrow, Vicky Cameron and 47 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

57 authors at 20 institutions in 11 countries.

Tessa SchillemansInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Vinicius TraganteDivision Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Buamina MaitusongInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Bruna GiganteDivision of Cardiovascular Medicine, Department of Medicine, Danderyd University Hospital, Karolinska Institutet, Stockholm, Sweden.
Sharon CresciCardiovascular Division, John T. Milliken Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, United States.
Federica LaguzziInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Max VikströmInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Mark RichardsDepartment of Medicine, Christchurch Heart Institute, University of Otago, Christchurch, New Zealand.
Anna PilbrowDepartment of Medicine, Christchurch Heart Institute, University of Otago, Christchurch, New Zealand.
Vicky CameronDepartment of Medicine, Christchurch Heart Institute, University of Otago, Christchurch, New Zealand.
Luisa FocoInstitute for Biomedicine, Eurac Research, Bolzano, Italy.
Robert N DoughtyHeart Health Research Group, The University of Auckland, Auckland, New Zealand.
Pekka KuukasjärviFinnish Cardiovascular Research Center - Tampere, Department of Cardio-Thoracic Surgery, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Hooman AllayeeDepartment of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
Jaana A HartialaDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
W H Wilson TangDepartment of Cardiovascular and Metabolic Sciences and Center for Microbiome and Human Health, Lerner Research Institute, Cleveland Clinic Ohio, Cleveland, OH, United States.
Leo-Pekka LyytikäinenDepartment of Clinical Chemistry, Fimlab Laboratories Ltd., Tampere, Finland.
Kjell NikusFinnish Cardiovascular Research Center - Tampere, Department of Cardiology, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Jari O LaurikkaFinnish Cardiovascular Research Center - Tampere, Department of Cardio-Thoracic Surgery, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Sundararajan SrinivasanDivision of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom.
Ify R MordiDivision of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, United Kingdom.
Stella TrompetDepartment of Internal Medicine, Leiden University Medical Center, Leiden, Netherlands.
Adriaan KraaijeveldDivision Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Jessica van SettenDivision Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Crystel M GijsbertsLaboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Anke H Maitland-van der ZeeAmsterdam University Medical Centers, Department of Respiratory Medicine, University of Amsterdam, Amsterdam, Netherlands.
Christoph H SaelyVorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria.
Yan GongCenter for Pharmacogenomics and Precision Medicine, Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, FL, United States.
Julie A JohnsonCenter for Pharmacogenomics and Precision Medicine, Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, FL, United States.
Rhonda M Cooper-DeHoffCenter for Pharmacogenomics and Precision Medicine, Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, FL, United States.
Carl J PepineDivision of Cardiovascular Medicine, College of Medicine, University of Florida, Gainesville, FL, United States.
Gavino CasuAzienda Ospedaliero Universitaria, Sassari, Italy.
Andreas LeihererVorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria.
Heinz DrexelVorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria.
Benjamin D HorneIntermountain Medical Center Heart Institute, Salt Lake City, UT, United States.
Sander W van der LaanCentral Diagnostics Laboratory, Division Laboratories, Pharmacy, and Biomedical Genetics, University Medical Center Utrecht, Utrecht, Netherlands.
Nicola MarzilianoMedicine Laboratory Unit, ASST Rhodense (Rho-Milano), Lombardy, Italy.
Stanley L HazenDepartment of Cardiovascular and Metabolic Sciences and Center for Microbiome and Human Health, Lerner Research Institute, Cleveland Clinic Ohio, Cleveland, OH, United States.
Juha SinisaloHeart and Lung Center, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Mika KähönenFinnish Cardiovascular Research Center - Tampere, Department of Clinical Physiology, Faculty of Medicine and Health Technology, Department of Clinical Physiology, Tampere University, Tampere, Finland.
Terho LehtimäkiDepartment of Clinical Chemistry, Fimlab Laboratories Ltd., Tampere, Finland.
Chim C LangDivision of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom.
Ralph BurkhardtInstitute of Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg, Germany.
Markus ScholzLIFE Research Center for Civilization Diseases, Institute for Medical Informatics, Statistics and Epidemiology, Leipzig University, Leipzig, Germany.
J Wouter JukemaDepartment of Cardiology, Leiden University Medical Center, Leiden, Netherlands.
Niclas ErikssonUppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.
Axel ÅkerblomUppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.
Stefan JamesUppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.
Claes HeldUppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.
Emil HagströmDepartment of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden.
John A SpertusSaint Luke´s Mid America Heart Institute, University of Missouri-Kansas City, Kansas City, MO, United States.
Ale AlgraDepartment of Neurology and Neurosurgery, Brain Centre Rudolf Magnus and Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands.
Ulf de FaireInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Agneta ÅkessonInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Folkert W AsselbergsDivision Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Riyaz S PatelFaculty of Population Health Sciences, Institute of Cardiovascular Science and Institute of Health Informatics, University College London, London, United Kingdom.
Karin LeanderInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Karolinska Institutet · SETampere University · FIUppsala University · SEUniversity Medical Center Utrecht · NLUniversity of Florida · USUniversity of Otago · NZGenomics (United Kingdom) · GBPrivate University in the Principality of Liechtenstein · LIUniversity of Southern California · USUtrecht University · NLAzienda Ospedaliero Universitaria di Sassari · ITCleveland Clinic · USCleveland Clinic Lerner College of Medicine · USEurac Research · ITHelsinki University Hospital · FIKarolinska University Hospital · SELeiden University Medical Center · NLLeipzig University · DENetherlands Heart Institute · NLStanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cohort studiescoronary heart diseasemeta-analysispolymorphismsPPARGC1ASNPs

Identifiers

PMID35812313
PMCPMC9260705
OpenAlexW4283321538

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.