Evidence map›Paper›PMID 35813490›Full record

ArticleRare tumors2022

Remission of a Primary, Recurrent Thoracic Ewing Sarcoma in a 74-year-old woman.

Robert M Tungate, Kristi Lara, Dakshesh Patel, Alexander Fedenko, James Hu

Abstract readCase Reports
In one paragraph

Article in Rare tumors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Robert M TungateUSC Norris Comprehensive Cancer Center and Hospital, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0002-9265-492X
Kristi LaraUSC Norris Comprehensive Cancer Center and Hospital, Los Angeles, CA, USA.
Dakshesh PatelUSC Norris Comprehensive Cancer Center and Hospital, Los Angeles, CA, USA.
Alexander FedenkoUSC Norris Comprehensive Cancer Center and Hospital, Los Angeles, CA, USA.
James HuUSC Norris Comprehensive Cancer Center and Hospital, Los Angeles, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ewing sarcoma is a primitive neuroectodermal tumor which seldom presents with primary disease in people over age 40 and outside of the appendicular or axial skeleton. We examine a case of primary thoracic Ewing Sarcoma diagnosed initially by CT-guided biopsy in a woman at the age of 74 years. The disease progressed after initial combined modality therapy consisting of neoadjuvant chemotherapy, surgical resection, and adjuvant radiation therapy and two additional courses of multiagent chemotherapy. After relapse of her disease, subsequent second- and third-line systemic agents which included chemotherapy and targeted agents were given with disease stabilization achieved now over 30 months from initial diagnosis. To our knowledge, this is the first report of a primary pulmonary Ewing sarcoma diagnosed in a patient greater than 70 years of age in whom multiple remissions have been achieved with tolerable toxicities.

Indexed as

adult Ewing SarcomaAskin’s tumorEwing sarcomaextraosseous Ewing Sarcomaprimary neuroectodermal tumorpulmonary Ewing Sarcomathoracic Ewing Sarcoma

Identifiers

PMID35813490
PMCPMC9260570

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.