ArticleFrontiers in psychiatry2022
Cognitive Impairment and Its Associated Factors in Older Adults Living in High and Low Altitude Areas: A Comparative Study.
Article in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Emerging trends in cognitive impairment and dementia among older populations in Asia: A systematic review.Journal of global health · 2024Pooled it
- Ratanasampil alleviates cognitive impairment in mice induced by chronic hypoxia by modulating inflammatory responses.Frontiers in immunology · 2026Article
- Cognitive Functions in High-altitude Tribal Population: Assessment Using the Montreal Cognitive Assessment (MoCA) Tool.Annals of neurosciences · 2025Article
- The association between sleep quality and cognitive impairment among a multi-ethnic population of middle-aged and older adults in Western China: a multi-center cross-sectional study.Frontiers in public health · 2025Article
- Hyperbaric Oxygen Improves Cognitive Impairment Induced by Hypoxia via Upregulating the Expression of Oleic Acid and MBOAT2 of Mice.Antioxidants (Basel, Switzerland) · 2024Article
- Assessment of Psychological and Social Fitness in Healthy Adults Permanently Living at Very High Altitude.International journal of environmental research and public health · 2023Observational
- A comparison of quality of life between older adults living in high and low altitude areas.Frontiers in public health · 2023Article
- The direct and mediating effects of cognitive impairment on the occurrence of falls: a cohort study based on community-dwelling old adults.Frontiers in medicine · 2023Article
- Sleep, short-term memory, and mood states of volunteers with increasing altitude.Frontiers in psychiatry · 2022Article
Corrections and comments
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Authors and funding
7 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Cognitive impairment is a major health concern in older adults. Few studies have examined the association between environmental factors and cognitive impairment, especially in high altitude areas. In this study, the prevalence of cognitive impairment in older adults living in high altitude was compared with those living in low altitude areas. Methods: This was a comparative study conducted at Qinghai (high altitude group), and Guangzhou (low altitude group), China. Cognition, depressive symptoms and quality of life (QOL) were assessed using the Montreal Cognitive Assessment (MoCA), Patient Health Questionnaire (PHQ-9) and WHO Quality of Life brief version-WHOQOL-BREF, respectively. Results: Altogether, 644 older adults (207 in Qinghai and 437 in Guangzhou) completed the assessment. The prevalence rate of cognitive impairment was 94.7% (95% CI: 91.6-97.7%) in older adults living in the high altitude area, while the corresponding figure was 89.2% (95% CI: 86.3-92.1%) in the low altitude area. After controlling for covariates, the high altitude group appeared more likely to have cognitive impairment (OR = 2.92, 95% CI: 1.23-6.91, Conclusion: This study found that cognitive impairment was more common among older adults living in the high altitude area. Regular screening and appropriate interventions should be provided to older adults in need.
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