Evidence map›Paper›PMID 35816737›Full record

Trial reportApplied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme2022

One week of overeating upregulates angiogenic and lipolytic gene expression in human subcutaneous adipose tissue from exercise trained and untrained adults.

Alison C Ludzki, Emily M Krueger, Jenna B Gillen, Natalie M Taylor, Darby O Middlebrook, Toree C Baldwin, Konstantinos C Karabetsos, Michael W Schleh, Jeffrey F Horowitz

Open access · greenAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Alison C LudzkiSchool of Kinesiology, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-6967-034X
Emily M KruegerSchool of Kinesiology, University of Michigan, Ann Arbor, MI, USA.
Jenna B GillenSchool of Kinesiology, University of Michigan, Ann Arbor, MI, USA.
Natalie M TaylorSchool of Kinesiology, University of Michigan, Ann Arbor, MI, USA.
Darby O MiddlebrookSchool of Kinesiology, University of Michigan, Ann Arbor, MI, USA.
Toree C BaldwinSchool of Kinesiology, University of Michigan, Ann Arbor, MI, USA.
Konstantinos C KarabetsosSchool of Kinesiology, University of Michigan, Ann Arbor, MI, USA.
Michael W SchlehSchool of Kinesiology, University of Michigan, Ann Arbor, MI, USA.
Jeffrey F HorowitzSchool of Kinesiology, University of Michigan, Ann Arbor, MI, USA.
University of Michigan · USUniversity of Toronto · CA

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAVID P OLSON · 2013 to 2026
$24.3M
Pilot and Feasibility (P and F) ProgramP30DK089503 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Joyce Lee · 2010 to 2026
$20.3M
Insulin sensitivity and fatty acid partitioning in skeletal muscle after exerciseR01DK077966 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HOROWITZ, JEFFREY F · 2010 to 2020
$4.9M
NIDDK NIH HHS P30 DK020572NIDDK NIH HHS P30 DK089503NIDDK NIH HHS R01 DK077966
6 · The paper itself

Abstract

Effective storage of excess energy in abdominal subcutaneous adipose tissue during periods of overeating may help attenuate weight-gain-related insulin resistance. The objective of this study was to assess changes in the expression of factors regulating abdominal subcutaneous adipose tissue storage capacity in response to a brief exposure to overeating in nonobese adults. Because exercise can alter the expression of genes involved in regulating adipose tissue storage capacity, we compared the responses to overeating in regular exercisers (EX,

Indexed as

Insulin ResistanceAdipose TissueAdultGene ExpressionHumansHyperphagiaIsophane Insulin, HumanPPAR gammaSubcutaneous FatSubcutaneous Fat, AbdominalIsophane Insulin, HumanPPAR gammaadipose tissueexercice physiqueexerciseexercise metabolismhumainshumansmétabolisme de l'exercicenutritionovereatingsuralimentationtissu adipeux

Identifiers

PMID35816737
PMCPMC10127504
OpenAlexW4285043437

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.