Evidence mapPaperPMID 35818559Full record

ReviewJACC. CardioOncology2022

Cardiometabolic Comorbidities in Cancer Survivors:

Leah L Zullig, Anthony D Sung, Michel G Khouri, Shelley Jazowski, Nishant P Shah, Andrea Sitlinger, Dan V Blalock, Colette Whitney, Robin Kikuchi, Hayden B Bosworth and 5 more

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in JACC. CardioOncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07513259 (Pre-Diagnosis GLP-1 Receptor Agonist Use and Post-Cancer Mortality in Adults With Obesity and Type 2 Diabetes), which is not on this map. Cited by 57 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 2 pooled it
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07513259 completednot on this map

Pre-Diagnosis GLP-1 Receptor Agonist Use and Post-Cancer Mortality in Adults With Obesity and Type 2 Diabetes: A Target Trial Emulation

TypeobservationalSponsorChung Shan Medical UniversityRan2018 to 2025Enrolled203,424ConditionsObesity & Overweight, Diabetes Mellitus Type 2, Neoplasms
3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 2 syntheses or guidelines pooled it, 81 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Article
  4. Article
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  6. Article
  7. Article
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  9. Article
  10. Article
  11. Research Priorities and Future Directions in Cardio-Oncology.Current treatment options in oncology · 2026
    Review
  12. Article
  13. Article
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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Leah L ZulligDepartment of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina, USA.
Anthony D SungDepartment of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Michel G KhouriDepartment of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Shelley JazowskiDepartment of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina, USA.
Nishant P ShahDepartment of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Andrea SitlingerDepartment of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Dan V BlalockCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Health Care System, Durham, North Carolina, USA.
Colette WhitneyDepartment of Psychiatry and Behavioral Sciences, Duke University, Durham, North Carolina, USA.
Robin KikuchiKeck School of Medicine, University of California-Los Angeles, Los Angeles, California, USA.
Hayden B BosworthDepartment of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina, USA.
Matthew J CrowleyCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Health Care System, Durham, North Carolina, USA.
Karen M GoldsteinCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Health Care System, Durham, North Carolina, USA.
Igor KlemDepartment of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Kevin C OeffingerDepartment of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Susan DentDepartment of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Duke University · USDurham VA Health Care System · USOregon State University Cascades · USUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are nearly 17 million cancer survivors in the United States, including those who are currently receiving cancer therapy with curative intent and expected to be long-term survivors, as well as those with chronic cancers such as metastatic disease or chronic lymphocytic leukemia, who will receive cancer therapy for many years. Current clinical practice guidelines focus on lifestyle interventions, such as exercise and healthy eating habits, but generally do not address management strategies for clinicians or strategies to increase adherence to medications. We discuss 3 cardiometabolic comorbidities among cancer survivors and present the prevalence of comorbidities prior to a cancer diagnosis, treatment of comorbidities during cancer therapy, and management considerations of comorbidities in long-term cancer survivors or those on chronic cancer therapy. Approaches to support medication adherence and potential methods to enhance a team approach to optimize care of the individual with cancer across the continuum of disease are discussed.

Indexed as

ACE, angiotensin-converting enzymeARB, angiotensin receptor blockercancer survivorshipcardiovascular comorbiditiescoordination of careCVD, cardiovascular diseaseLDL-C, low-density lipoprotein cholesterolmedication adherencemultidisciplinary care

Identifiers

PMID35818559
PMCPMC9270612
OpenAlexW4283259168

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.