ArticleSports medicine (Auckland, N.Z.)2022
Factors Influencing Substrate Oxidation During Submaximal Cycling: A Modelling Analysis.
Article in Sports medicine (Auckland, N.Z.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Acute effects of resistance exercise on skeletal muscle glycogen depletion: A systematic review and meta-analysis.Physiological reports · 2025Pooled it
- The OMNIVEG Study: Effects of Transitioning from a Traditional to a Vegan Mediterranean Diet on Fat Oxidation During Exercise.Nutrients · 2025Trial
- No evidence of improvements in energy metabolism after 1 week of nitrate and citrulline co-supplementation in elite rowers.European journal of applied physiology · 2025Trial
- A comprehensive review of the physiology and evidence base to guide the use of ergogenic and medical supplements for enhanced cycling performance.Journal of the International Society of Sports Nutrition · 2026Review
- Energy Substrate Utilization and Body Composition Following Exercise Preconditioning During Alternate-Day Fasting and Concurrent Exercise in Mice.Metabolites · 2026Article
- A Narrative Review of the High-Carbohydrate Fueling Revolution (≥ 100 g/h) in the Professional Peloton.Sports medicine (Auckland, N.Z.) · 2026Review
- Response to "Comment on "Exercise Testing for Metabolic Flexibility: Time for Protocol Standardization".Sports medicine - open · 2025Article
- Review
- Myopathic Symptoms and Exercise Tolerance in Adolescent Patients With Long-Chain Fatty Acid Oxidation Disorders.Journal of inherited metabolic disease · 2025Article
- Carbohydrate ingestion during prolonged exercise blunts the reduction in power output at the moderate-to-heavy intensity transition.European journal of applied physiology · 2025Article
- Exercise Testing for Metabolic Flexibility: Time for Protocol Standardization.Sports medicine - open · 2025Article
- Article
- A Novel Method to Predict Carbohydrate and Energy Expenditure During Endurance Exercise Using Measures of Training Load.Sports medicine (Auckland, N.Z.) · 2025Article
- A gluten-free diet does not alter performance outcomes in nonceliac athletes undergoing sprint interval training: a pilot trial.Frontiers in sports and active living · 2025Article
- Upregulation of Xbp1 in NPY/AgRP neurons reverses diet-induced obesity and ameliorates leptin and insulin resistance.Neuropeptides · 2024Article
- Predicting daily recovery during long-term endurance training using machine learning analysis.European journal of applied physiology · 2024Article
- Daily rhythms in metabolic and locomotor behaviour of prematurely ageing PolgA mice.FEBS open bio · 2024Article
- Iron deficiency in patients with a Fontan circulation and its impact on exercise capacity.Open heart · 2024Article
- Resting Metabolic Rate and Substrate Utilization during Energy and Protein Availability in Male and Female Athletes.Metabolites · 2024Article
- Restoring glucose balance: Conditional HMGB1 knockdown mitigates hyperglycemia in a Streptozotocin induced mouse model.Heliyon · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMultiple factors influence substrate oxidation during exercise including exercise duration and intensity, sex, and dietary intake before and during exercise. However, the relative influence and interaction between these factors is unclear.
objectivesOur aim was to investigate factors influencing the respiratory exchange ratio (RER) during continuous exercise and formulate multivariable regression models to determine which factors best explain RER during exercise, as well as their relative influence.
methodsData were extracted from 434 studies reporting RER during continuous cycling exercise. General linear mixed-effect models were used to determine relationships between RER and factors purported to influence RER (e.g., exercise duration and intensity, muscle glycogen, dietary intake, age, and sex), and to examine which factors influenced RER, with standardized coefficients used to assess their relative influence.
resultsThe RER decreases with exercise duration, dietary fat intake, age, VO
conclusionVariability in RER during exercise cannot be fully accounted for by models incorporating a range of participant, diet, exercise, and physiological characteristics. To better understand what influences substrate oxidation during exercise further research is required on older subjects and females, and on other factors that could explain additional variability in RER.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.