Evidence map›Paper›PMID 35834949›Full record

ReviewCurrent opinion in structural biology2022

Scanning x-ray microdiffraction: In situ molecular imaging of tissue and materials.

Jiliang Liu, Lee Makowski

Abstract readReview
In one paragraph

Review in Current opinion in structural biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. The BioSAXS laboratory of the ITACA.SB Research Infrastructure.Journal of applied crystallography · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jiliang LiuThe European Radiation Synchrotron Facility (ESRF), Grenoble, France.
Lee MakowskiBioengineering Department, Northeastern University, Boston, MA, USA. Electronic address: l.makowski@northeastern.edu.

Funding

Fibrillar polymorphs in human brain tissueRF1AG079946 · NIA · NORTHEASTERN UNIVERSITY · PI MAKOWSKI, LEE · 2023 to 2023
$2.1M
Localization of fibrillar polymorphs in human brain tissueR21AG068972 · NIA · NORTHEASTERN UNIVERSITY · PI MAKOWSKI, LEE · 2020 to 2020
$432k
NIA NIH HHS R21 AG068972NIA NIH HHS RF1 AG079946
6 · The paper itself

Abstract

Scanning x-ray microdiffraction of complex tissues and materials is an emerging method for the study of macromolecular structures in situ, providing information on the way molecular constituents are arranged and interact with their microenvironment. Acting as a bridge between high-resolution images of individual constituents and lower resolution microscopies that generate global views of material, scanning microdiffraction provides an approach to study the functioning of complex tissues across multiple length scales. Here, we discuss the methodology, summarize results from recent studies, and discuss the potential of the technique for future studies coordinated with other biophysical techniques.

Indexed as

Molecular ImagingX-Ray DiffractionX-Rays

Identifiers

PMID35834949
PMCPMC11317818

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.