Evidence mapPaperPMID 35836730Full record

ArticleCardiology research2022

Outcomes of Heart Failure in COVID-19 Patients: An Appalachian Experience.

Huzefa Bhopalwala, Aelia Akbar, Nakeya Dewaswala, Lauren Wisnieski, Abdul Mannan Khan Minhas, Akbar Hussain, Vinayak Mishra, Sourbha S Dani, Andrew Kolodziej, Gaurang Vaidya and 5 more

Open access · diamondAbstract read
In one paragraph

Article in Cardiology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Pathophysiology and Management of Heart Failure in the Elderly.The International journal of angiology : official publication of the International College of Angiology, Inc · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 3 countries.

Huzefa BhopalwalaDepartment of Internal Medicine, Appalachian Regional Healthcare, Whitesburg, KY, USA.
Aelia AkbarDepartment of Internal Medicine, Appalachian Regional Healthcare, Whitesburg, KY, USA.
Nakeya DewaswalaDepartment of Cardiovascular Disease, University of Kentucky, Lexington, KY, USA.
Lauren WisnieskiDepartment of Public Health and Research, Lincoln Memorial University, Harrogate, TN, USA.
Abdul Mannan Khan MinhasDepartment of Internal Medicine, Forrest General Hospital, Hattiesburg, MS, USA.
Akbar HussainJinnah Sindh Medical University, Karachi, Pakistan.
Vinayak MishraGrant Government Medical College and Sir J.J. Group of Hospitals, Mumbai, India.
Sourbha S DaniDepartment of Cardiovascular Disease, Lahey Hospital and Medical Center, Burlington, MA, USA.
Andrew KolodziejDepartment of Cardiovascular Disease, University of Kentucky, Lexington, KY, USA.
Gaurang VaidyaDepartment of Cardiovascular Disease, University of Kentucky, Lexington, KY, USA.
Abhishek KulkarniDivision of Cardiology, Department of Internal Medicine, Southern Illinois University School of Medicine, Springfield, IL, USA.
Jonathan PiercyDepartment of Internal Medicine, Appalachian Regional Healthcare, Whitesburg, KY, USA.
Shyam GantiDepartment of Internal Medicine, Appalachian Regional Healthcare, Whitesburg, KY, USA.
Nagabhishek MokaDepartment of Internal Medicine, Appalachian Regional Healthcare, Whitesburg, KY, USA.
Adnan BhopalwalaDepartment of Internal Medicine, Appalachian Regional Healthcare, Whitesburg, KY, USA.
Appalachian Regional Healthcare · USUniversity of Kentucky · USForrest General Hospital · USGovernment Medical College · INJinnah Sindh Medical University · PKLahey Hospital and Medical Center · USLincoln Memorial University · USSouthern Illinois University School of Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The Southeastern rural areas of the USA have a higher prevalence of heart failure (HF). Coronavirus disease 2019 (COVID-19) infection is associated with poor outcomes in patients with HF. Our study aimed to compare the outcomes of hospitalized HF patients with and without COVID-19 infection specifically in rural parts of the USA. Methods: We conducted a retrospective cohort study of HF patients with and without COVID-19 hospitalized in Southeastern rural parts of the USA by using the Appalachian Regional Healthcare System. Analyses were stratified by waves from April 1, 2020 to May 31, 2021, and from June 1, 2021 to October 19, 2021. Results: Of the 14,379 patients hospitalized with HF, 6% had concomitant COVID-19 infection. We found that HF patients with COVID-19 had higher mortality rate compared to those without COVID-19 (21.8% versus 3.8%, respectively, P < 0.01). Additionally, hospital resource utilization was significantly higher in HF patients with COVID-19 compared to HF patients without COVID-19 with intensive care unit (ICU) utilization of 21.6% versus 13.8%, P < 0.01, mechanical ventilation use of 17.3% versus 6.2%, P < 0.01, and vasopressor/inotrope use of 16.8% versus 7.9%, P < 0.01. A lower percentage of those with COVID-19 were discharged home compared to those without a COVID-19 diagnosis (63.4% versus 72.0%, respectively). There was a six-fold greater odds of dying in the first wave and seven-fold greater odds of dying in the second wave. Conclusions: Our study confirms previous findings of poor outcome in HF patients with COVID-19. There is a need for review of healthcare resources in rural hospitals which already face numerous healthcare challenges.

Indexed as

CohortCoronavirusCOVID-19Heart failureMortalitySARS-CoV-2Survival

Identifiers

PMID35836730
PMCPMC9239503
OpenAlexW4283078935

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.