Evidence map›Paper›PMID 35836945›Full record

ArticleFrontiers in medicine2022

Cardiovascular Biomarkers for Prediction of in-hospital and 1-Year Post-discharge Mortality in Patients With COVID-19 Pneumonia.

Lukas J Motloch, Peter Jirak, Diana Gareeva, Paruir Davtyan, Ruslan Gumerov, Irina Lakman, Aleksandr Tataurov, Rustem Zulkarneev, Ildar Kabirov, Benzhi Cai and 8 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 4 countries.

Lukas J MotlochUniversity Clinic for Internal Medicine II, Paracelsus Medical University, Salzburg, Austria.
Peter JirakUniversity Clinic for Internal Medicine II, Paracelsus Medical University, Salzburg, Austria.
Diana GareevaCardiovascular Disease in COVID-19, International Research Network, Ufa, Russia.
Paruir DavtyanCardiovascular Disease in COVID-19, International Research Network, Ufa, Russia.
Ruslan GumerovCardiovascular Disease in COVID-19, International Research Network, Ufa, Russia.
Irina LakmanCardiovascular Disease in COVID-19, International Research Network, Ufa, Russia.
Aleksandr TataurovScientific Laboratory for the Socio-Economic Region Problems Investigation, Bashkir State University, Ufa, Russia.
Rustem ZulkarneevDepartment of Internal Diseases, Bashkir State Medical University, Ufa, Russia.
Ildar KabirovDepartment of Urology, Bashkir State Medical University, Ufa, Russia.
Benzhi CaiCardiovascular Disease in COVID-19, International Research Network, Ufa, Russia.
Bairas ValeevDepartment of Internal Diseases, Bashkir State Medical University, Ufa, Russia.
Valentin PavlovCardiovascular Disease in COVID-19, International Research Network, Ufa, Russia.
Kristen KoppUniversity Clinic for Internal Medicine II, Paracelsus Medical University, Salzburg, Austria.
Uta C HoppeUniversity Clinic for Internal Medicine II, Paracelsus Medical University, Salzburg, Austria.
Michael LichtenauerUniversity Clinic for Internal Medicine II, Paracelsus Medical University, Salzburg, Austria.
Lukas FiedlerUniversity Clinic for Internal Medicine II, Paracelsus Medical University, Salzburg, Austria.
Rudin PistulliDepartment of Cardiology I, Coronary and Peripheral Vascular Disease, Heart Failure, University Hospital Munster, Munster, Germany.
Naufal ZagidullinCardiovascular Disease in COVID-19, International Research Network, Ufa, Russia.
Bashkir State Medical University · RUParacelsus Medical University · ATBashkir State University · RUFachhochschule Wiener Neustadt · ATSecond Affiliated Hospital of Harbin Medical University · CNUniversity Hospital Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: While COVID-19 affects the cardiovascular system, the potential clinical impact of cardiovascular biomarkers on predicting outcomes in COVID-19 patients is still unknown. Therefore, to investigate this issue we analyzed the prognostic potential of cardiac biomarkers on in-hospital and long-term post-discharge mortality of patients with COVID-19 pneumonia. Methods: Serum soluble ST2, VCAM-1, and hs-TnI were evaluated upon admission in 280 consecutive patients hospitalized with COVID-19-associated pneumonia in a single, tertiary care center. Patient clinical and laboratory characteristics and the concentration of biomarkers were correlated with in-hospital [Hospital stay: 11 days (10; 14)] and post-discharge all-cause mortality at 1 year follow-up [FU: 354 days (342; 361)]. Results: 11 patients died while hospitalized for COVID-19 (3.9%), and 11 patients died during the 1-year post-discharge follow-up period ( Conclusion: In patients hospitalized with Covid-19 pneumonia, elevated levels of VCAM-1 at admission were associated with in-hospital mortality, while ST2 and hs-TnI might predict post-discharge mortality in long term follow-up.

Indexed as

cardiovascular biomarkersCOVID-19long COVID-19post-discharge mortalitysST2VCAM-1

Identifiers

PMID35836945
PMCPMC9273888
OpenAlexW4283662364

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.