Evidence mapPaperPMID 35837984Full record

ArticleDiabetes, obesity & metabolism2022

Lived experience of CamAPS FX closed loop system in youth with type 1 diabetes and their parents.

Korey K Hood, Natasha Garcia-Willingham, Sarah Hanes, Molly L Tanenbaum, Julia Ware, Charlotte K Boughton, Janet M Allen, Malgorzata E Wilinska, Martin Tauschmann, Louise Denvir and 17 more

Abstract read
In one paragraph

Article in Diabetes, obesity & metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Trial
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  9. Article
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  11. Review
  12. Review
  13. A Systematic Review of Commercial Hybrid Closed-Loop Automated Insulin Delivery Systems.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2023 · on this map
    Review
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Korey K HoodStanford University School of Medicine, Stanford Diabetes Research Center, Stanford, California, USA.ORCID 0000-0001-5730-7749
Natasha Garcia-WillinghamStanford University School of Medicine, Stanford Diabetes Research Center, Stanford, California, USA.
Sarah HanesStanford University School of Medicine, Stanford Diabetes Research Center, Stanford, California, USA.
Molly L TanenbaumStanford University School of Medicine, Stanford Diabetes Research Center, Stanford, California, USA.
Julia WareWellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
Charlotte K BoughtonWellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.ORCID 0000-0003-3272-9544
Janet M AllenWellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
Malgorzata E WilinskaWellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
Martin TauschmannWellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
Louise DenvirDepartment of Paediatric Diabetes and Endocrinology, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Ajay ThankamonyDepartment of Paediatrics, University of Cambridge, Cambridge, UK.
Fiona CampbellDepartment of Paediatric Diabetes, Leeds Children's Hospital, Leeds, UK.
R Paul WadwaBarbara Davis Center for Childhood Diabetes, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Bruce A BuckinghamStanford University School of Medicine, Stanford Diabetes Research Center, Stanford, California, USA.
Nikki DavisDepartment of Paediatric Endocrinology and Diabetes, Southampton Children's Hospital, Southampton General Hospital, Southampton, UK.
Linda A DiMeglioDepartment of Pediatrics, Division of Pediatric Endocrinology and Diabetology, Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Nelly MaurasDivision of Endocrinology, Diabetes & Metabolism, Nemours Children's Health, Jacksonville, Florida, USA.
Rachel E J BesserOxford University Hospitals NHS Foundation Trust, NIHR Oxford Biomedical Research Centre, Oxford, UK.
Atrayee GhatakAlder Hey Children's Hospital, Liverpool, UK.
Stuart A WeinzimerDepartment of Pediatrics, Yale University, New Haven, Connecticut, USA.
D Steven FoxDepartment of Pharmaceutical and Health Economics, School of Pharmacy, University of Southern California, Los Angeles, California, USA.
Lauren KanapkaThe Jaeb Center for Health Research, Tampa, Florida, USA.
Craig KollmanThe Jaeb Center for Health Research, Tampa, Florida, USA.
Judy SibayanThe Jaeb Center for Health Research, Tampa, Florida, USA.
Roy W BeckThe Jaeb Center for Health Research, Tampa, Florida, USA.
Roman HovorkaWellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
DAN05 Consortium

Funding

Yale Diabetes Research CenterP30DK045735 · YALE UNIVERSITY · 1993 to 2025
$10.2M
Yale Clinical and Translational Science AwardUL1TR001863 · YALE UNIVERSITY · 2025 to 2025
$9.9M
NCATS NIH HHS UL1 TR001863NIDDK NIH HHS P30 DK045735NIDDK NIH HHS UC4 DK108520
6 · The paper itself

Abstract

aimTo examine changes in the lived experience of type 1 diabetes after use of hybrid closed loop (CL), including the CamAPS FX CL system. MATERIALS AND

methodsThe primary study was conducted as an open-label, single-period, randomized, parallel design contrasting CL versus insulin pump (with or without continuous glucose monitoring). Participants were asked to complete patient-reported outcomes before starting CL and 3 and 6 months later. Surveys assessed diabetes distress, hypoglycaemia concerns and quality of life. Qualitative focus group data were collected at the completion of the study.

resultsIn this sample of 98 youth (age range 6-18, mean age 12.7 ± 2.8 years) and their parents, CL use was not associated with psychosocial benefits overall. However, the subgroup (n = 12) using the CamAPS FX system showed modest improvements in quality of life and parent distress, reinforced by both survey (p < .05) and focus group responses. There were no negative effects of CL use reported by study participants.

conclusionsClosed loop use via the CamAPS FX system was associated with modest improvements in aspects of the lived experience of managing type 1 diabetes in youth and their families. Further refinements of the system may optimize the user experience.

Indexed as

Diabetes Mellitus, Type 1AdolescentBlood GlucoseBlood Glucose Self-MonitoringChildHumansHypoglycemic AgentsInsulinInsulin Infusion SystemsParentsQuality of LifeTreatment OutcomeBlood GlucoseHypoglycemic AgentsInsulin

Identifiers

PMID35837984
PMCPMC9804666

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.