ArticleEFORT open reviews2021
A guide to regional analgesia for Total Knee Arthroplasty.
Article in EFORT open reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Continuous femoral nerve block as pain management following total knee arthroplasty: a systematic review.Archives of orthopaedic and trauma surgery · 2025Pooled it
- Clinical effects of interspace between the popliteal artery and capsule of the posterior knee block with multimodal analgesia for total knee arthroplasty: a systematic review and meta-analysis.Archives of orthopaedic and trauma surgery · 2023Pooled it
- Tourniquet-less total knee arthroplasty does not negatively affect cement penetration: a double-blinded randomized controlled trial.International orthopaedics · 2025Trial
- Single-injection nerve blocks for total knee arthroplasty: femoral nerve block versus femoral triangle block versus adductor canal block-a randomized controlled double-blinded trial.Archives of orthopaedic and trauma surgery · 2023Trial
- Effect of Femoral Nerve Block with Different Concentrations of Chloroprocaine on Early Postoperative Rehabilitation Training After Total Knee Arthroplasty.Medical science monitor : international medical journal of experimental and clinical research · 2023Trial
- Ultrasound-Guided Genicular Nerve Block: Novel Clinical Role for Postoperative Knee Replacement Surgery Pain Management.Current pain and headache reports · 2026Review
- Popliteal Plexus Block as a Potential Alternative to IPACK Block in Total-Knee Arthroplasty: Anatomical Rationale, Clinical Evidence, and Ergonomic Advantages.Journal of clinical medicine · 2026Review
- Article
- Thromboembolic complications were not different between intravenous and epidural analgesia after unilateral knee arthroplasty under neuraxial anesthesia: a propensity-score matched analysis.Perioperative medicine (London, England) · 2026Article
- Pain trajectory after total knee arthroplasty (TKA) with prolonged use of outpatient adductor canal catheters.Journal of anesthesia and translational medicine · 2025Article
- Article
- Validation of a Novel Landmark-guided Intra-articular Postero-medial Surgeon-administered Injection Technique.Arthroplasty today · 2025Article
- Analgesia Nociception Index Monitoring in Management of Perioperative Analgesia in Total Knee Arthroplasty Surgeries with Femoral Nerve Block.Medicina (Kaunas, Lithuania) · 2025Article
- Anesthetic considerations for joint replacement surgery in hemophilic arthropathy: a comprehensive review.Anesthesia and pain medicine · 2024Review
- Article
- A Retrospective Comparison of Clinical Efficacy between Multimodal Analgesia and Patient-Controlled Epidural Analgesia in Patients Undergoing Total Knee Arthroplasty.Medicina (Kaunas, Lithuania) · 2023Article
- Evaluation of Postoperative Analgesic Efficacy of Ultrasound-Guided Suprainguinal Fascia Iliaca Block in Knee Arthroplasty: Prospective, Randomized, Feasibility Study.Journal of clinical medicine · 2023Article
- Review
- Another regional analgesic block for total knee arthroplasty!Saudi journal of anaesthesiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Regional analgesia has been introduced successfully into the postoperative pain management after total knee arthroplasty, reducing pain scores, opioid use and adverse effects. Combination of regional analgesia techniques is associated with better pain management and lower side effects than single regional techniques. Adductor canal block provides good analgesia and considerably lower detrimental effect in muscular strength than femoral nerve block, enhancing surgical recovery. Infiltration techniques may have equivalent analgesic effect than epidural analgesia and peripheral nerve blocks, however there should be awareness of dose dependent toxicity. Novel long-acting local anesthetics role for regional analgesia is still to be determined, and will require larger randomized trials to support its advantage over traditional local anesthetics.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.