Evidence map›Paper›PMID 35844403›Full record

ArticleSaudi journal of biological sciences2022

Antiproliferative and apoptotic potential of Glycyrrhizin against HPV16+ Caski cervical cancer cells: A plausible association with downreguation of HPV E6 and E7 oncogenes and Notch signaling pathway.

Afza Ahmad, Rohit Kumar Tiwari, Prakriti Mishra, Ali G Alkhathami, Tahani M Almeleebia, Mohammad Y Alshahrani, Irfan Ahmad, Rawan Amer Asiri, Noura M Alabdullah, Mohamed Hussien and 2 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Saudi journal of biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
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  4. Plants (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Afza AhmadDepartment of Biosciences, Integral University, Kursi Road, Lucknow 226026, Uttar Pradesh, India.
Rohit Kumar TiwariDepartment of Biosciences, Integral University, Kursi Road, Lucknow 226026, Uttar Pradesh, India.
Prakriti MishraDepartment of Biosciences, Integral University, Kursi Road, Lucknow 226026, Uttar Pradesh, India.
Ali G AlkhathamiDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, P.O. Box 61413, Abha 9088, Saudi Arabia.
Tahani M AlmeleebiaDepartment of Clinical Pharmacy, College of Pharmacy, King Khalid University, P.O. Box 61413, Abha 9088, Saudi Arabia.
Mohammad Y AlshahraniDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, P.O. Box 61413, Abha 9088, Saudi Arabia.
Irfan AhmadDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, P.O. Box 61413, Abha 9088, Saudi Arabia.
Rawan Amer AsiriDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, P.O. Box 61413, Abha 9088, Saudi Arabia.
Noura M AlabdullahCollege of Pharmacy, King Khalid University, P.O. Box 61413, Abha 9088, Saudi Arabia.
Mohamed HussienDepartment of Chemistry, Faculty of Science, King Khalid University, P.O. Box 9004, Abha 61413, Saudi Arabia.
Mohd SaeedDepartment of Biology, College of Sciences, University of Hail, Hail, Saudi Arabia.
Irfan Ahmad AnsariDepartment of Biosciences, Integral University, Kursi Road, Lucknow 226026, Uttar Pradesh, India.
King Khalid University · SAIntegral University · INUniversity of Ha'il · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical cancer (CCa) is the second most frequent carcinoma in females and human papilloma virus (HPV) oncoproteins are regarded as one of the critical etiological agent. Despite recent advances in screening and management of CCa, still it remains the deadliest carcinoma as advanced and metastatic stages are mostly incurable. This urges for the development of newer therapeutic interventions. The current was aimed to investigate the antiproliferative and apoptotic potential of glycyrrhizin (

Indexed as

ApoptosisCell cycleCervical cancerGlycyrrhizinHPV oncoproteinsNotch signaling pathway

Identifiers

PMID35844403
PMCPMC9280173
OpenAlexW4210306969

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.