Evidence map›Paper›PMID 35844635›Full record

ArticleFrontiers in chemistry2022

Synthesis and Anticancer Activity of Rhopaladins' Analog RPDPD Against the HeLa Human Cervical Cancer Cell Line.

Feng Chen, Hong-Mei Wang, Ling-Qi Kong, Qin-Hua Chen, Li-Na Ke, He-Liu Dai, Xiao-Hua Zeng

Open access · goldAbstract read
In one paragraph

Article in Frontiers in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Feng ChenSinopharm Dongfeng General Hospital, Hubei University of Medicine, Shiyan, China.
Hong-Mei WangHubei Key Laboratory of Wudang Local Chinese Medicine Research, School of Pharmaceutical Sciences, Hubei University of Medicine, Shiyan, China.
Ling-Qi KongHubei Key Laboratory of Wudang Local Chinese Medicine Research, School of Pharmaceutical Sciences, Hubei University of Medicine, Shiyan, China.
Qin-Hua ChenShenzhen Baoan Authentic TCM Therapy Hospital, Shenzhen, China.
Li-Na KeSinopharm Dongfeng General Hospital, Hubei University of Medicine, Shiyan, China.
He-Liu DaiSinopharm Dongfeng General Hospital, Hubei University of Medicine, Shiyan, China.
Xiao-Hua ZengSinopharm Dongfeng General Hospital, Hubei University of Medicine, Shiyan, China.
Hubei University of Medicine · CNChina National Pharmaceutical Group Corporation (China) · CNDongfeng General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heterocyclic compounds were widely used in many domains; pyrrolidone is a derivative of heterocycles that can be used to synthesize anticancer drugs. A new fluorine-containing rhopaladins' analog(

Indexed as

2-aroyl-4-arylidene-5-oxopyrrolidinecytotoxicity evaluationHPV E6/E7 mRNArhopaladins’ analogsynthesisTIMP3/MMP3 pathway

Identifiers

PMID35844635
PMCPMC9277706
OpenAlexW4283591762

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.