SynthesisFrontiers in cardiovascular medicine2022
Prognostic Value of Left Atrial Strain in Heart Failure: A Systematic Review and Meta-Analysis.
Synthesis in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic value of left atrial strain in acute and chronic heart failure: A meta-analysis.ESC heart failure · 2025Pooled it
- Left atrial dysfunction can independently predict exercise capacity in patients with chronic heart failure who use beta-blockers.BMC cardiovascular disorders · 2023Trial
- Left Atrial Reservoir Strain and Heart Failure Rehospitalization Burden in Acute Heart Failure With Atrial Fibrillation.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Strain imaging in heart failure: from early detection to prognostic assessment.ESC heart failure · 2026Review
- Article
- Impaired left atrial strain is associated with new-onset atrial fibrillation and adverse clinical outcomes in primary care patients.Heart rhythm O2 · 2026Article
- Role of imaging techniques in monitoring atrial cardiomyopathy and atrial failure: a scientific statement.ESC heart failure · 2026Review
- Clinical and prognostic impact of left atrial strain in non-ischemic cardiomyopathies.The international journal of cardiovascular imaging · 2026Review
- Association of left atrial strain and fibrin clot properties in patients with heart failure and severe mitral regurgitation undergoing transcatheter edge-to-edge repair.Journal of thrombosis and thrombolysis · 2026Article
- Prognostic and functional value of left atrial indices in advanced heart failure.Cardiovascular ultrasound · 2026Article
- Left atrial strain parameters for predicting new-onset atrial fibrillation: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2026Review
- Left Atrial Reservoir Strain in Cardiovascular and Systemic Disease: Advances and Clinical Applications From Physiology to Practice.Reviews in cardiovascular medicine · 2025Review
- Changes in Cardiac Function and Exercise Capacity Following Ferric Carboxymaltose Administration in HFrEF Patients with Iron Deficiency.Diagnostics (Basel, Switzerland) · 2025Article
- Assessing the Use of Left Atrial Strain Before and After Treadmill Exercise Stress Echocardiography.Echocardiography (Mount Kisco, N.Y.) · 2025Article
- The Prognostic Implication of Left Atrial Strain Parameters with Conventional Left Atrial Parameters for the Prediction of Adverse Outcomes in Asian Patients with Hypertrophic Cardiomyopathy-An Echocardiographic Study.Journal of cardiovascular development and disease · 2025Article
- Time's imprint on the left atrium: aging and atrial myopathy.The journal of cardiovascular aging · 2025Article
- Left Atrial Strain-Current Review of Clinical Applications.Diagnostics (Basel, Switzerland) · 2025Review
- Left atrial reservoir strain as a predictor of cardiac dysfunction in a murine model of pressure overload.Acta physiologica (Oxford, England) · 2025Article
- Incidence of new-onset HFpEF across CKD stages and Its association with cardio-renal, inflammatory, and fibrotic biomarkers.Frontiers in cardiovascular medicine · 2025Article
- Left Atrial Structural and Functional Changes in Adults with Congenital Septal Defects and Paroxysmal Atrial Fibrillation.Journal of clinical medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Heart failure (HF) is a global health problem with high morbidity and mortality. Recently, the association between peak atrial longitudinal strain (PALS) and clinical outcomes of HF has gained increasing attention. Our aim was to systematically assess the prognostic value of PALS for adverse events in HF. Methods: PubMed, Embase, and Scopus databases were systematically searched from inception to 30 April 2022. Studies in which PALS was assessed to predict adverse outcomes in adult patients with HF were included. Study selection, quality assessment, and data extraction were performed independently by two authors. The primary endpoints were all-cause death and cardiac hospitalization. Results: Among 7,787 patients in 17 included studies, 3,029 (38.9%) experienced the primary endpoint. Patients with events had lower PALS than those without events [weighted mean difference (WMD) 6.17, 95% confidence interval (CI) 3.09-9.26, Conclusion: Peak atrial longitudinal strain was an independent predictor for all-cause mortality and cardiac hospitalization in patients with HF, highlighting the clinical importance of left atrial (LA) deformation in the prognosis of HF. Systematic Review Registration: [www.crd.york.ac.uk/prospero/], identifier [CRD42020185034].
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.