Evidence map›Paper›PMID 35845147›Full record

ArticlePharmaceutical chemistry journal2022

Viral Safety Issues in the Production and Manufacturing of Human Immunoglobulin Preparations from Equine Plasma/Serum.

V V Mashin, A N Sergeev, N N Martynova, A A Sergeev, K A Lys'ko, A O Raikov, V V Kataeva, N V Zagidullin

Open access · bronzeAbstract read
In one paragraph

Article in Pharmaceutical chemistry journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

V V MashinJoint Stock Company Microgen Scientific Industrial Company for Immunobiological Medicines, 10 2nd Volkonskii Per., Moscow, 127473 Russia.
A N SergeevJoint Stock Company Microgen Scientific Industrial Company for Immunobiological Medicines, 10 2nd Volkonskii Per., Moscow, 127473 Russia.
N N MartynovaJoint Stock Company Microgen Scientific Industrial Company for Immunobiological Medicines, 10 2nd Volkonskii Per., Moscow, 127473 Russia.
A A SergeevMoscow Office of AVVA Pharmaceuticals Ltd., 4/3 Aviamotornaya St., Office 8, Moscow, 111116 Russia.
K A Lys'koJoint Stock Company Microgen Scientific Industrial Company for Immunobiological Medicines, 10 2nd Volkonskii Per., Moscow, 127473 Russia.
A O RaikovJoint Stock Company Microgen Scientific Industrial Company for Immunobiological Medicines, 10 2nd Volkonskii Per., Moscow, 127473 Russia.
V V KataevaJoint Stock Company Microgen Scientific Industrial Company for Immunobiological Medicines, 10 2nd Volkonskii Per., Moscow, 127473 Russia.
N V ZagidullinJoint Stock Company Microgen Scientific Industrial Company for Immunobiological Medicines, 10 2nd Volkonskii Per., Moscow, 127473 Russia.
Research Center of Neurology · RUBaranov Central Institute of Aviation Motor Development · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current Russian and foreign pharmacopoeias either do not provide any information about existing types of viral diseases in horses or do not present it in full. Data of modern domestic and foreign literature was used to prepare the most complete list of viruses that cause equine diseases including 36 infectious agents, 25 of which are pathogenic for humans, 13 of the 25 of which are widespread throughout Russia. Information is provided on the magnitudes of the disease incubation periods (which are most often within one month), the external clinical signs of these diseases (which can also be asymptomatic), and the maximum possible concentrations of viruses in the blood of horses with these diseases (which can reach 8 log conventional units/mL of blood). This information is offered for use in critical production stages of heterologous immunoglobulin drugs for medical use to assure viral safety.

Indexed as

distribution areaequine immunoglobulinhorseviral infectionvirus concentration

Identifiers

PMID35845147
PMCPMC9274627
OpenAlexW4285028194

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.