Evidence map›Paper›PMID 35845540›Full record

ArticleAnnals of translational medicine2022

Evaluation on clinical performance of the new low-value platelet measurement mode (PLT-8X) of BC-6800Plus.

Yimin Shen, Dongmei Liu, Yong Wang, Jun Cao, Shuaishuai Zhang, Hui Wen, Qiuqiu Dong, Dong Zheng, Jun Qiu

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Article in Annals of translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Yimin Shen *Center of Clinical Laboratory, the First Affiliated Hospital of Soochow University, Suzhou, China.
Dongmei Liu *Center of Clinical Laboratory, the First Affiliated Hospital of Soochow University, Suzhou, China.
Yong WangCenter of Clinical Laboratory, the First Affiliated Hospital of Soochow University, Suzhou, China.
Jun CaoCenter of Clinical Laboratory, the First Affiliated Hospital of Soochow University, Suzhou, China.
Shuaishuai ZhangCenter of Clinical Laboratory, the First Affiliated Hospital of Soochow University, Suzhou, China.
Hui WenCenter of Clinical Laboratory, the First Affiliated Hospital of Soochow University, Suzhou, China.
Qiuqiu DongCenter of Clinical Laboratory, the First Affiliated Hospital of Soochow University, Suzhou, China.
Dong ZhengCenter of Clinical Laboratory, the First Affiliated Hospital of Soochow University, Suzhou, China.
Jun QiuCenter of Clinical Laboratory, the First Affiliated Hospital of Soochow University, Suzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The accuracy of low-value platelet (PLT) testing is a key reference for clinical decision-making regarding PLT transfusion or surgery. This study aimed to evaluate the capability to detect low-value PLT of the 8 times optical platelet counting (PLT-8X) mode of the BC-6800Plus auto hematology analyzer. Methods: Totally 40 fresh anticoagulated venous whole blood samples with PLT ≤50×10 Results: The precision low-value PLT in PLT-8X mode was significantly superior to that in PLT-I (P<0.0001); and the correlation coefficient of PLT-8X mode compared with the reference method of flow cytometer was 0.992. The expected bias at the low-value medical decision levels (5×10 Conclusions: The PLT-8X mode of the BC-6800Plus auto hematology analyzer has extremely low detection sensitivity for low-value PLTs in anticoagulated venous whole blood samples. With good linearity, its precision and accuracy can sufficiently meet the needs for hematology laboratory use, and it can effectively help clinicians to accurately diagnose and treat patients with thrombopenia-related diseases.

Indexed as

8 times optical platelet counting (PLT-8X)BC-6800Plusperformance evaluationplatelet counting reference method (PLT counting reference method)thrombocytopenia

Identifiers

PMID35845540
PMCPMC9279826

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.