Evidence map›Paper›PMID 35846507›Full record

ArticleRadiology case reports2022

A severe presentation of breakthrough infection caused by the Omicron variant with radiological findings of COVID-19 pneumonia in an elderly woman.

Barbara Brogna, Chiara Capasso, Giovanni Fontanella, Elio Bignardi

Open access · goldAbstract readCase Reports
In one paragraph

Article in Radiology case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Barbara BrognaDepartment of Radiology, San Giuseppe Moscati Hospital, Contrada Amoretta, 83100 Avellino, Italy.
Chiara CapassoPharmacology Department, "Frangipane" Hospital, ASL Avellino, Via V. Emanuele, 83031 Ariano Irpino, Italy.
Giovanni FontanellaDepartment of Radiology, Sacred Hear of Jesus Hospital- Fatebenefratelli, 82100, Benevento, Italy.
Elio BignardiRadiology Unit, "Cotugno Hospital", Naples, Via Quagliariello 54, 80131 Naples, Italy.
Azienda Ospedaliera S.Giuseppe Moscati · ITFatebenefratelli Hospital · ITOspedale D. Cotugno · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Omicron variant of COVID-19 is characterized by exceptional transmissibility and by immune evasion with the ability infect people with naturally acquired or vaccine-induced immunity. However, lung involvement is poorly reported in patients who resulted positive by this new COVID-19 variant. COVID-19 breakthrough infections are defined as COVID-19 infection in fully vaccinated patients. Herein, we present a case of breakthrough infection in an elderly woman who came in emergency with dyspnea and with findings of COVID-19 pneumonia on chest computed tomography. The patient was vaccinated with a booster dose of an mRNA vaccine some months earlier and the Omicron variant was detected on real-time reverse-transcription polymerase chain reaction. However, the patient's condition remained stable. For our knowledge we report the first case with lung involvement due to Omicron variant in an elderly after the booster dose of mRNA vaccine. This case highlights as COVID-19 breakthrough infections may represent some concerns in the elderly patients in presence of virus variants.

Indexed as

COVID-19ElderlyImmunosenescenceOmicron variantVaccines

Identifiers

PMID35846507
PMCPMC9275445
OpenAlexW4285082259

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.