Evidence map›Paper›PMID 35847377›Full record

ArticleMaterials today. Bio2022

A 3D bioprinted nano-laponite hydrogel construct promotes osteogenesis by activating PI3K/AKT signaling pathway.

Sheng Miao, Jinru Zhou, Bin Liu, Xing Lei, Taoran Wang, Xiaotian Hao, Pengzhen Cheng, Hao Wu, Yue Song, Guoxian Pei and 1 more

Abstract read
In one paragraph

Article in Materials today. Bio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. LaponiteMolecules (Basel, Switzerland) · 2024
    Review
  18. Article
  19. Review
  20. Materials today. Bio · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sheng MiaoDepartment of Orthopedics, Xijing Hospital, Air Force Medical University, Xi'an, 710032, China.
Jinru ZhouDepartment of Radiology, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, 471000, China.
Bin LiuDepartment of Orthopedics, General Hospital of Northern Theater Command, Shenyang, 110015, China.
Xing LeiDepartment of Orthopedics, Linyi People's Hospital, Linyi, 276002, China.
Taoran WangDepartment of Orthopedics, Xijing Hospital, Air Force Medical University, Xi'an, 710032, China.
Xiaotian HaoCollege of Life Sciences, Northwest University, Xi'an, 710069, China.
Pengzhen ChengDepartment of Orthopedics, Xijing Hospital, Air Force Medical University, Xi'an, 710032, China.
Hao WuDepartment of Orthopedics, Xijing Hospital, Air Force Medical University, Xi'an, 710032, China.
Yue SongDepartment of Orthopedics, Fourth Medical Center of PLA General Hospital, Beijing, 100048, China.
Guoxian PeiDepartment of Orthopedics, Xijing Hospital, Air Force Medical University, Xi'an, 710032, China.
Long BiDepartment of Orthopedics, Xijing Hospital, Air Force Medical University, Xi'an, 710032, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Development of nano-laponite as bioinks based on cell-loaded hydrogels has recently attracted significant attention for promoting bone defect repairs and regeneration. However, the underlying mechanisms of the positive function of laponite in hydrogel was not fully explored. In this study, the effect of 3D bioprinted nano-laponite hydrogel construct on bone regeneration and the potential mechanism was explored

Indexed as

BioprintingCell densityNano-laponiteOsteogenesisSignal pathway

Identifiers

PMID35847377
PMCPMC9278073

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.