Evidence mapPaperPMID 35847973Full record

ReviewFrontiers in molecular biosciences2022

Molecular Mechanisms of Epigenetic Regulation, Inflammation, and Cell Death in ADPKD.

Ewud Agborbesong, Linda Xiaoyan Li, Lu Li, Xiaogang Li

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
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  16. A synthetic agent ameliorates polycystic kidney disease by promoting apoptosis of cystic cells through increased oxidative stress.Proceedings of the National Academy of Sciences of the United States of America · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ewud AgborbesongDepartment of Internal Medicine, Mayo Clinic, Rochester, MN, United States.
Linda Xiaoyan LiDepartment of Internal Medicine, Mayo Clinic, Rochester, MN, United States.
Lu LiDepartment of Internal Medicine, Mayo Clinic, Rochester, MN, United States.
Xiaogang LiDepartment of Internal Medicine, Mayo Clinic, Rochester, MN, United States.
Mayo Clinic in Arizona · US

Funding

NIDDK NIH HHS R01 DK126662NIDDK NIH HHS R01 DK129241
6 · The paper itself

Abstract

Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder, which is caused by mutations in the

Indexed as

ADPKDcell deathepigeneticsinflammationpost-translational modifications

Identifiers

PMID35847973
PMCPMC9277309
OpenAlexW4285820344

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.