Evidence map›Paper›PMID 35848616›Full record

ReviewAmerican journal of physiology. Cell physiology2022

Kir5.1 channels: potential role in epilepsy and seizure disorders.

Alexander Staruschenko, Matthew R Hodges, Oleg Palygin

Open access · greenAbstract readReview
In one paragraph

Review in American journal of physiology. Cell physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Repeated seizures lead to progressive ventilatory dysfunction in SSJournal of applied physiology (Bethesda, Md. : 1985) · 2023
    Article
  6. Article
  7. Observational
  8. Special collection on inward rectifying KAmerican journal of physiology. Cell physiology · 2023
    Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Alexander StaruschenkoDepartment of Molecular Pharmacology and Physiology, University of South Florida, Tampa, Florida.ORCID 0000-0002-5190-8356
Matthew R HodgesDepartment of Physiology and Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin.
Oleg PalyginDivision of Nephrology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.ORCID 0000-0002-3680-5527
Medical College of Wisconsin · USMedical University of South Carolina · USUniversity of South Florida · US

Funding

Progressive seizure-induced cardiorespiratory dysfunction in a novel mutant rat model of seizure disorderR01HL122358 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI HODGES, MATTHEW ROBERT · 2015 to 2024
$4.3M
Renal ion channels in the control of blood pressureR35HL135749 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI STARUSCHENKO, ALEXANDER · 2017 to 2023
$3.6M
Role of basolateral K channels in renal salt handling and BP controlR01DK126720 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI PALYGIN, OLEG · 2021 to 2024
$1.5M
Transport and metabolism in the kidneyI01BX004024 · VA · JAMES A. HALEY VA MEDICAL CENTER · PI STARUSCHENKO, ALEXANDER · 2019 to 2025
–
BLRD VA I01 BX004024NHLBI NIH HHS R01 HL122358NHLBI NIH HHS R35 HL135749NIDDK NIH HHS R01 DK126720
6 · The paper itself

Abstract

Inwardly rectifying potassium (Kir) channels are broadly expressed in many mammalian organ systems, where they contribute to critical physiological functions. However, the importance and function of the Kir5.1 channel (encoded by the

Indexed as

EpilepsyPotassium Channels, Inwardly RectifyingAnimalsHumansKidneyKir5.1 ChannelMammalsMicePotassiumRatsKCNJ16 protein, humanKcnj16 protein, mouseKir5.1 ChannelPotassiumPotassium Channels, Inwardly Rectifyingdeafnesskcnj10kcnj16SIDS

Identifiers

PMID35848616
PMCPMC9448276
OpenAlexW4285731377

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.