Evidence map›Paper›PMID 35853265›Full record

ArticleCell calcium2022

LIPID transfer proteins regulate store-operated calcium entry via control of plasma membrane phosphoinositides.

Gergo Gulyas, Marek K Korzeniowski, Carlos Ernesto Bastián Eugenio, Luis Vaca, Yeun Ju Kim, Tamas Balla

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell calcium, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Gergo GulyasSection on Molecular Signal Transduction, Program for Developmental Neuroscience, Eunice Kennedy Shriver NICHD, National Institutes of Health, Bethesda, MD, 20892, USA.
Marek K KorzeniowskiSection on Molecular Signal Transduction, Program for Developmental Neuroscience, Eunice Kennedy Shriver NICHD, National Institutes of Health, Bethesda, MD, 20892, USA; Department of Anatomy, Physiology, and Genetics, Uniformed Services University, Bethesda, MD, USA.
Carlos Ernesto Bastián EugenioSection on Molecular Signal Transduction, Program for Developmental Neuroscience, Eunice Kennedy Shriver NICHD, National Institutes of Health, Bethesda, MD, 20892, USA; Instituto de Fisiología Celular, Universidad Nacional Autónoma de Mexico City DF, CP, 04510, USA.
Luis VacaInstituto de Fisiología Celular, Universidad Nacional Autónoma de Mexico City DF, CP, 04510, USA.
Yeun Ju KimSection on Molecular Signal Transduction, Program for Developmental Neuroscience, Eunice Kennedy Shriver NICHD, National Institutes of Health, Bethesda, MD, 20892, USA.
Tamas BallaSection on Molecular Signal Transduction, Program for Developmental Neuroscience, Eunice Kennedy Shriver NICHD, National Institutes of Health, Bethesda, MD, 20892, USA. Electronic address: ballat@mail.nih.gov.
Eunice Kennedy Shriver National Institute of Child Health and Human Development · USNational Institutes of Health · USUniformed Services University of the Health Sciences · USUniversidad Nacional Autónoma de México · MX

Funding

Phosphoinositide-calcium Signaling In Cell RegulationZIAHD000196 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI BALLA, TAMAS · 2009 to 2025
$26.3M
PHOSPHOINOSITIDE-CALCIUM SIGNALING IN CELL REGULATIONZ01HD000196 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI BALLA, TAMAS · 1998 to 2008
$1.9M
Intramural NIH HHS Z01 HD000196
6 · The paper itself

Abstract

The ER-resident proteins STIM1 together with the plasma membrane (PM)-localized Orai1 channels constitute the molecular components of the store-operated Ca

Indexed as

CalciumPhosphatidylinositolsCalcium SignalingCell MembraneEndoplasmic ReticulumORAI1 ProteinStromal Interaction Molecule 1CalciumORAI1 ProteinPhosphatidylinositolsStromal Interaction Molecule 1CalciumERLipid transfer proteinsMembrane contact sitesPhosphatidylinositolPhosphoinositidesPlasma membrane

Identifiers

PMID35853265
PMCPMC9444960
OpenAlexW4285046329

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.